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Chinese Journal of Virology ; (6): 464-471, 2008.
Article de Chinois | WPRIM | ID: wpr-334777

RÉSUMÉ

The N gene and genome promoter nucleotide sequence of a Chinese Peste des petits rumiants virus (PPRV) ("China/Tib/Gej/07-30") was firstly determined. The length of N gene was 1689 nucleotides with a single open reading frame (ORF). The nucleotide and deduced amino acid sequence was compared with the homologous region of other PPRV isolates. The nucleotide sequence of the "China/Tib/Gej/07-30" was 91.7%-97.6% identical to other PPRV isolates, while a homology of 94.9%-98.5% could be observed at the amino acids level. The N gene encoded a protein of 525 amino acids. Several sequence motifs were identified on the basis of conservation in the PPRVs and the morbilliviruses. The genome length of promoter region was 107 nucleotides with 91.8%-98.2% identity to other PPRV isolates. Phylogenetic analysis showed that the "China/Tib/Gej/07-30" belonged to the Asian lineage.


Sujet(s)
Animaux , Femelle , Séquence d'acides aminés , Séquence nucléotidique , Chine , Génome viral , Maladies des chèvres , Virologie , Capra , Données de séquences moléculaires , Protéines nucléocapside , Chimie , Génétique , Peste des petits ruminants , Virologie , Virus de la peste des petits ruminants , Chimie , Classification , Génétique , Phylogenèse , Régions promotrices (génétique) , Alignement de séquences , Analyse de séquence
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