[Clinical features and treatment in cushing's disease. About 18 cases]

We report a retrospective study about 18 Cushing's diseases colliged in the department of endocrinology at Charles Nicolle hospital in 24 years. The mean age was 33, 7 years with a male-female ratio of 4/14 Diagnosis was established on adrenocorticotropin hormone analysis and pituitary imaging. Transsphenoidal adenomectomy was related in 8 cases of Cushing's disease, it was sussessful in 5 patients [62.5%]. Bilateral adrenalectomy was performed in three cases