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Chinese Journal of Experimental and Clinical Virology ; (6): 95-97, 2008.
Article Dans Chinois | WPRIM | ID: wpr-254133

Résumé

<p><b>OBJECTIVE</b>To study the clinical and laboratory characteristics of adult Japanese encephalitis (JE) patients in a JE outbreak in Yuncheng, Shanxi Province in 2006.</p><p><b>METHOD</b>All the clinical data from the Second People's Hospital in Yuncheng city were analyzed, part of patients' sera and cerebrospinal fluid were tested by serology and RT-PCR.</p><p><b>RESULTS</b>The majority of patients were middle-aged and elderly, 77.8% (35/45) of the total cases were more than 40 years old. Severe and fulminating type cases accounted for 60.0% (27/45). Most patients had underlying diseases. IgM antibody to JE virus (JEV) in serum was positive in each of the 45 patients analyzed and 4-fold or greater rise in sera neutralization antibody titer were found in convalescent serum. JEV nucleic acid was positive in part of cerebrospinal fluid specimens.</p><p><b>CONCLUSION</b>Viral encephalitis emerged in Yuncheng city, Shanxi Province was Japanese encephalitis B, and most of the cases belonged to elderly group.</p>


Sujets)
Adolescent , Adulte , Sujet âgé , Sujet âgé de 80 ans ou plus , Enfant , Enfant d'âge préscolaire , Femelle , Humains , Mâle , Adulte d'âge moyen , Jeune adulte , Anticorps antiviraux , Sang , Chine , Épidémiologie , Épidémies de maladies , Virus de l'encéphalite japonaise (espèce) , Génétique , Allergie et immunologie , Encéphalite japonaise , Sang , Liquide cérébrospinal , Épidémiologie , Immunoglobuline M , Sang , Tests de neutralisation , ARN viral , Génétique , RT-PCR
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