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Journal of Korean Medical Science ; : 525-528, 2009.
Article Dans Anglais | WPRIM | ID: wpr-36930

Résumé

Primary adrenal lymphoma is a very rare extranodal lymphoma; its clinical features consist of a high incidence of bilateral adrenal involvement and diffuse large B-cell lymphoma. We report a patient with primary bilateral adrenal diffuse large B-cell lyphoma who achieved complete remission with R-CHOP (rituximab-cyclophosphamide, doxorubicin, vincristine, and prednisone) chemotherapy. A 52-yr-old man presented with fever and progressive fatigue for 3 months. Computed tomography (CT) scans of the abdomen and pelvis demonstrated large bilateral adrenal masses, and a needle biopsy of the left adrenal mass revealed diffuse large B-cell lymphoma. After 6 cycles of R-CHOP chemotherapy, CT scans showed no residual disease. To our knowledge, this is the second report to date of a patient with primary bilateral adrenal diffuse large B-cell lymphoma who achieved complete remission using R-CHOP chemotherapy.


Sujets)
Humains , Mâle , Adulte d'âge moyen , Tumeurs de la surrénale/traitement médicamenteux , Anticorps monoclonaux/usage thérapeutique , Protocoles de polychimiothérapie antinéoplasique/usage thérapeutique , Cyclophosphamide/usage thérapeutique , Doxorubicine/usage thérapeutique , Association de médicaments , Lymphome B diffus à grandes cellules/traitement médicamenteux , Tomographie par émission de positons , Prednisone/usage thérapeutique , Tomodensitométrie , Vincristine/usage thérapeutique
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