Résumé
Consanguinity is very common in the Sudanese society. There is a lack of studies on consanguinity and its impact on genetic diseases in Sudan. In this study we correlated Disorders of Sexual developments [DSDs], as an example of genetic conditions, in relation with consanguinity. A cohort of twenty six cases from 15 Sudanese families were diagnosed with DSD between the years 2008-2010, Diagnosis was done in Al-Neelian Medical Research Centre, Al-Neelain University, Sudan in collaboration with the University of L beck, Germany. Parental consanguinity was seen in 70%, 10% were not consanguineous while 20% did not provide a detailed family pedigree. There is strong association between consanguinity and inheritance of DSDs in the Sudan, which is expected to be higher than that reported in the literature about non-consanguineous DSDs from western countries