[Investigation of changes in levels of liver trans-aminases in measles affected patients hospitalized in Be'sat hospital in 1379]

Background: One of measles manifestations -especially in adolescents- is liver malfunction which can vary from just changes in liver enzymes to hepatitis with prominent jaundice. It is important to screen hepatitis patients in order to special medical treatment and avoidance of prescribing hapatotoxic drugs and some pain relief medications. In addition, patients of such complications are high risk for long duration of hospitalization and secondary complications and long duration of the disease

Materials and methods: This was a cross-sectional study of 172 patients selected from 180 patients with clinical measles admitted in Be'sat hospital of NAHAJA. CBC and liver enzymes were checked

Results: Patients aged between 18 to 24 years. Mean of hospitalization time was 6.48 +/- 2.37days and ranged from 2 to 14. Mean of white blood count was 4153.85 +/-1706.08 and ranged from 1700 to 13000. PMNs percentage was 61.01+/-16.27 in mean and ranged from 26% to 89%. Mean of total PMN count was 2591.38+/-1409.42 [from 513 to 10270]. ALT [SGPT] was 40.86+/-33.68 in mean [from 10 to 280]. Mean of AST [SGOT] was 53.23+/- 35.76 ranged from 15 to 250. Total bilirobin was 0.9+/-0.31 [from 0.2 to 2.1] in mean. Mean of direct bilirobin was 0.2+/-0.8 ranged from 0.1 to 0.8. ALKP was 195.19+/-88.6 [from 41 to 590]. 9.5 %of patients [16 patients] had liver malfunction [2 times increase of enzymes levels]. No one had jaundice at the time of admit. Comparison of evaluation of lab values of the patients with duration of hospitalization with Pearson test, only in two cases PMN percentage and total PMN had significant relation [P<0.05]

Conclusions: When measles patients had no complications such as secondary bacterial infections and had no history of hepatotoxic drugs, increase in liver enzymes levels is mild and had no significant clinical interest

Investigation of changes in levels of liver trans-aminases in measles affected patients hospitalized in Be'sat hospital in 1379

One of measles manifestations -especially in adolescents- is liver malfunction which can vary from just changes in liver enzymes to hepatitis with prominent jaundice. It is important to screen hepatitis patients in order to special medical treatment and avoidance of prescribing hapatotoxic drugs and some pain relief medications. In addition, patients of such complications are high risk for long duration of hospitalization and secondary complications and long duration of the disease. This was a cross-sectional study of 172 patients selected from 180 patients with clinical measles admitted in Be'sat hospital of NAHAJA. CBC and liver enzymes were checked. Patients aged between 18 to 24 years. Mean of hospitalization time was 6.48 +/- 2.37days and ranged from 2 to 14. Mean of white blood count was 4153.85 +/- 1706.08 and ranged from 1700 to 13000. PMNs percentage was 61.01 +/- 16.27 in mean and ranged from 26% to 89%. Mean of total PMN count was 2591.38 +/- 1409.42 [from 513 to 10270]. ALT [SGPT] was 40.86 +/- 33.68 in mean [from 10 to 280]. Mean of AST [SGOT] was 53.23+7- 35.76 ranged from 15 to 250. Total bilirobin was 0.9 +/- 0.31 [from 0.2 to 2.1] in mean. Mean of direct bilirobin was 0.2 +/- 0.8 ranged from 0.1 to 0.8. ALKP was 195.19+7-88.6 [from 41 to 590]. 9.5%of patients [16 patients] had liver malfunction [2 times increase of enzymes levels]. No one had jaundice at the time of admit. Comparison of evaluation of lab values of the patients with duration of hospitalization with Pearson test, only in two cases PMN percentage and total PMN had significant relation [P<0.05]. When measles patients had no complications such as secondary bacterial infections and had no history of hepatotoxic drugs, increase in liver enzymes levels is mild and had no significant clinical interest