Study of foetal hemoglobin [HbF] and glucose-6-phosphate dehydrogenase [G6PD] in children of hilly areas of Abbottabad

Two hundred and thirty apparently healthy children [150 males and 80 females] and 120 refractory anaemic children [70 males and 50 females] of different age groups were investigated for Foetal Haemoglobin [HbF], HbA2 and Glucose-6-Phosphate Dehydrogenase [G6PD] for a period of 18 months. Age ranged between 8 months to 14 ears. The mean Hb of healthy and anaemic children was 13.9 g/dl and 6.4 g/dl respectively. The mean HbF levels were 0.917, in healthy and 13.6% in anaemic children. Twenty four percent of anaemic children had elevated HbF wind most of them showed associated increase of HbA2. Ten cases of thalassaemia major and 19 cases of thalassemia minor were identified. Among the healthy children, three males and one female were found to be CdFPD deficient, while in anaemic children, 8 males and 4 females had G6PD deficiency. No relationship was observed between HbF and G6PD. However, an unusual case was found who had inherited G6PD deficiency from father and beta thalassaemia from the mother's side

Incidence of urinary tract infection during pregnancy

Incidence of Urinary tract infection was determined in 164 pregnant women presented at DHQ Teaching Hospital, Abbottabad. The cases with significant bacteriuria [> 10 5 organisms/ml of Urine] were 9.7% of total. 76% of the patients were less than 30 years of age with mean of 28 years. In the symptomatic group the frequency of UTI was 12.5% while in the asymptomatic group it was about 4.0%. Pyuria was found in 13.4% of the total cases. Albumin and Glucose in Urine were found to be 6% and 3% respectively. The organisms isolated were E. Coli [56.3%] Staphylococcus [25.0%] Klebsiella Spp [12.5%] and proteus Spp [6.2%]. Most of them were sensitive to Minocin, gentamicin, claforan, whereas the sensitivity to Amoxil, Dalacin, Fosfomycin and Doxycyclin was variable

Bacteriological study of urinary tract infections in healthy school going children of Hazara division

The frequency of urinary tract infection was studied among 500 healthy school children aged 6 to 13 years. Only 2.2% of the cases showed significant bacteriuria [105 organisms/ml urine]. The organisms isolated were E. Coli [36.5%], Staphylococcus [36.5%], Klebsiella [9%], Streptococcus [9%], and Micrococcus [9%]. Most of them were sensitive to Ampi cillin, Kanamycin, Fosfomycin, Nitrofurantoin, Gentamycin

Bacteriological study of drinking water in district Abbottabad

Seventy samples were collected from various sources of drinking water in Abbottabad Disrtict, to study the quality of such water. Out of all samples, faecal contamination was found in 57.2% of samples, while 18.6% of the samples were found sterile having less than 10 bacilli per 100 ml. It was noted that water from 76.2% spring, 100% streams, 44.0% taps and 50% shallow wells and faecal contamination. The common organism isolated were echerichia coli 57.2%, klebsiella 14.3% pseudomonas 1%, preoteus 1.4% and micrococci 1.4