RÉSUMÉ
A prospective study examined the safety, efficacy and labour outcome in 436 women undergoing labour induction using intravaginal prostaglandin E2. Women with singleton pregnancies [235 nulliparas and 201 multiparas] were recruited if they had a clinically unfavourable cervix, and indications for induction. The mean [standard deviation] interval from initiation to delivery was statistically significantly shorter in multiparas than nulliparas: 13.5 hours [SD 1.8] versus 15.5 hours [SD 2.4]. No more than 2 x 3 mg tablets were needed to achieve a clinically feasible cervix for amniotomy. The overall need for oxytocin augmentation of labour was 42%, significantly higher in nulliparas [47%] than multiparas [35%]. Intrapartum complications, caesarean section and perinatal deaths showed no statistically significant differences between the groups
Sujet(s)
Femelle , Humains , Prostaglandines E , Prostaglandines E/administration et posologie , Études prospectives , Administration par voie vaginale , OcytocineRÉSUMÉ
To assess the effectiveness of intravaginal misoprostol for second trimester uterine evacuation, we studied 70 women with singleton pregnancies complicated by fetal malformation or dead fetuses. Participants received 200 microgram misoprostol administered at 4-hour intervals. Gestations with dead fetuses had a shorter induction-abortion interval [14.2 hours, st and ard deviation [SD] 4.3] than those with live, malformed fetuses [20.2 hours, SD 7.3] [P< 0.001]. The abortion rate was significantly higher for gestations with dead fetuses [92.1%] than those with live, malformed fetuses [68.8%] [P< 0.05]. There were no major complications and no significant difference in the incidence of side-effects. All women aborted within 38 hours. Administration of misoprostol is an effective clinical method to terminate second trimester, complicated pregnancy
Sujet(s)
Femelle , Humains , Abortifs , Administration par voie vaginale , Mort foetale/thérapie , Misoprostol/effets indésirables , Grossesse , Deuxième trimestre de grossesseRÉSUMÉ
The efficacy, safety and outcome of prostagl and in [PG]E2 was compared with Foley catheter for labour induction in gr and multiparous women. At a hospital in Jordan, 147 women with Bishop score = 5 were r and omized to receive 3 mg PGE2 vaginal tablets [n = 75] or 50 mL intracervical Foley catheter [n = 72]. The change in Bishop score was significantly higher in the PGE2 group than the catheter group, and time from induction to delivery was significantly shorter in the PGE2 group. Significantly more women needed oxytocin for labour augmentation in the catheter than the PGE2 group and fetal distress was significantly more frequent. For gr and multiparas, PGE2 vaginal tablets may be preferable for ripening the cervix as well as for labour induction
Sujet(s)
Adulte , Femelle , Humains , Administration par voie vaginale , Accouchement (procédure)/méthodes , Souffrance foetale/étiologie , Âge gestationnel , Hôpitaux militaires , Accouchement provoqué/méthodes , Âge maternel , ParitéRÉSUMÉ
To determine the microbiology of wound infection following caesarean section and to evaluate the use of Gram stain for the predicton of subsequent microbiological culture results, 1319 surgical wounds were followed up. We did Gram stains and cultures on exudates from open wounds and on aspirates if the wounds had demonstrable fluid collection. Incidence of post-caesarean wound infection was 8.1%. Ninety-three [86.9%] of 107 infected wounds were culture positive, with Staphylococcus aureus the most frequently found organism [42%]. Organisms seen by Gram stain yielded a sensitivity of 96.6%, specificity of 88.9%, positive predictive value of 97.7% and negative predictive value of 84.2% when used to predict positive culture results for bacterial wound infection