Pseudomesotheliomatous lung carcinoma of poorly differentiated large cell type: a case report and review of the literature

A 46-year-old female presented with a 20-day history of right pleuritic chest pain and progressive shortness of breath. She was found to have a right pleural based malignancy initially thought to be a malignant mesothelioma but staining with the mesothelioma tumor markers calretinin, HBME-1 and CK5/6, was negative. Some epitheial markers were positive and microscopically it was consistent with a poorly differentiated large-cell carcinoma. The case was diagnosed as a pseudomesotheliomatous lung carcinoma of poorly differentiated large-cell type