carcinoembryonic antigen level in malignant and benign serous effusions

Carcinoembryonic antigen [CEA] level was estimated in malignant and benign pleural and ascitic serous effusions. It was also estimated in the corresponding serum samples of the same patients. It was found that CEA level was very high in malignant effusions with positive cytology and in the corresponding serum samples. While, in malignant effusions with negative cytology, CEA level showed no significant change when compared with the benign group. Within the benign group itself, CEA was significantly higher in bacterial effusions than in other types of effusions. Proper evaluation of the test was made, discussed and compared with other reports on the same topic

Study of effects of insulin on haemostatic system in obese and control subjects

The haemostatic effect of intravenous insulin administration was investigated in obese and control subjects. A hypercoagulability state was elucidated by enhancement of thromboplastin generation and increase of platelet adhesiveness. Stimulation of catecholamine release is supposed to be an underlying factor. An associated enhancement of fibrinolysis was observed and was less marked in obese than control subjects. Such findings point to paradoxical effects of insulin on the haemostatic parameters