4 [3H] - quinazolinone derivatives as beta adrenergic blockers

B-aryl-s-triazoline-5-thiones reacted with alpha-haloketones to give the S-substituted derivatives 2, which were cyclized to substituted thiazolo [3,2-b]-s-triazoles 3 and 4. 2-[3-Aryl-2-propenoyl]-3-methyl-6-pheny!-thiazoIo [3,2-b]-s-triazoles [6] were prepared and their behaviour toward amine derivatives and benzanilide were investigated. The structure of the products were elucidated by chemical and physical routes