Comparative study of diclofenac sodium with adrenaline for prevention of intra operative miosis

To determined the efficacy of adrenaline, when used in irrigation solution for prevention of preoperative meioses during cataract surgery. It is a comparative study. Study was conducted at Ophthalmology unit of Abbasi Shaheed Hospital from January, 2004 to July 2004. One hundred [100] patients were selected, who had cataracts without associated problems. In 50 patients Diclofenac Sodium 1% was used pre operatively 4 times together with tropicanamide 1% eye drops. In other 50 patients only tropicanamide 1% eye drops were used to dilate the pupil. In these patients, adrenaline 1 ml [1:100] diluted in 500 ml of ringers solution was used during surgery. In all these extracapsular cataract extraction with IOL were performed. Pupils were studied at the start and at the end of surgery. Before surgery pupil size was 8mm approximately. At the end of surgery pupil size was 5.5 mm with diclofenac sodium and 6.5 mm in those cases where adrenaline added in irrigation solution. Delivery of the large lens through semidiluted pupils leads to some trauma to the sphincter pupillae which reacts by constriction even in presence of adrenaline and use of diclofenac sodium 1% eye drops. This type of pupillary constriction is less in presence of adrenaline in infusion irrigation solution during surgery

After removal of pterygium role of mitomycin and conjunctival autograft

The major problem after pterygium removal is recurrences and complication of the therapy. Purpose of this study is to find out appropriate surgical technique, which has lower rate of recurrences and minimum complications. Perspective. A comparative study of two surgical treatment of pterygium removal has been carried out in Abbasi Shaheed Hospital and Karachi Medical and Dental College. The study period was 12 months starting from February 2003. A total no. of 102 patients, [130 eyes] with primary pterygium are included in this study. These patients were placed into group-l and group-II. Group I consist of 82 patients [114 eyes]. In this group pterygium excision was done will bare sclera technique and mitomycin c eye drops were used post operatively 2 times daily for 3 days. The group II consists of 20 patients [20 eyes]. In these patient the pterygium excision combined with conjunctival auto graft. The follow up ranged 6-9 months. The mean follow up time was upto 7.32 months. The pterygium recurred in 1 patient [1.36%] in group I, and in 2 patients [13.33%] in group II, complication observed in group I patients are irritability and lacrimation in 16 patients [21.9%] avascularized sclera in 12 patients [16.43%], conjunctival granuloma in 2 patients [2.73%] and superficial punctate keratitis in 1 patients [1.36%]. In group II patients conjunctival cyst formed in 2 patients [13.33%], conjunctival granuloma in 1 patient [6.66%] and wound gaping was observed in 1 patient [6.6%].The study indicates that post operative use of 0.02% mitomycin c eye drops twice daily for 3 days is a safe and effective treatment for prevention of recurrence of pterygium