RÉSUMÉ
Background: Premature babies, particularly those with very low birth weight (VLBW), are at a higher risk of developing congenital hypothyroidism. The inadequate development of the hypothalamic-pituitary axis in preterm infants contributes to the higher prevalence of this condition in this population. However, the optimal screening and treatment protocols for congenital hypothyroidism in preterm newborns remain unclear.Methods: This was a hospital-based observational study conducted over a period of 18 months. The study included 150 preterm babies born at the Sri Adichunchanagiri hospital and research centre. Non-probability sampling was used to select the study subjects. Data on demographic and clinical factors were collected from mothers and newborns. Blood samples were collected at day 3 of life to estimate thyroid-stimulating hormone levels. Correlations between TSH levels and various parameters were analyzed using statistical methods.Results: The study found that the prevalence of congenital hypothyroidism in preterm newborns was 2%. The mean TSH level at day 3 was 7.56 mIU/L, and 9.3% of cases had TSH levels above 20 mIU/l. Significant associations were found between high TSH levels and primiparity, vaginal delivery, and maternal gestational diabetes mellitus. There was an inverse correlation between TSH levels and gestational age, birth weight, and Apgar scores at 1 and 5 minutes.Conclusions: The study revealed a prevalence of congenital hypothyroidism of 2% in preterm newborns. Risk factors such as primiparity, vaginal delivery, and maternal GDM were associated with high TSH levels. These findings highlight the importance of screening and early detection of congenital hypothyroidism in premature babies to improve outcomes.
RÉSUMÉ
Background: Many adolescent girls die prematurely due to various preventable or treatable reasons, and many more suffer from chronic ill-health and disability. The objective of this study was to assess the nutritional status, gynaecological problems, and psychological problems of adolescent girls attending the Paediatric OPD and ward. The aim was to study the prevalence of malnutrition in adolescent girls attending paediatric OPD and ward.Methods: A cross-sectional hospital-based study was conducted on adolescent girls attending Paediatric OPD and ward of Adichunchanagiri institute of medical sciences and research centre, B. G. Nagara from November 2019 to November 2020. A total of 374 adolescent girls (10-17 years) were enrolled. Clinical examination was done after recording their weight and height. Body Mass Index was computed.Results: Mean age of the study participants was 13.05 years, and majority of them were from low socioeconomic status. Around 41.2% of the fathers had semi-skilled jobs, and 19.3% of the mothers had clerical jobs, shop owners, or farmers. About 71.1% of the adolescents attained menarche with a mean age of 13.2 ± 0.11 years. 62% had normal BMI, followed by 25.1% with underweight, overweight in 9.4%, and obese in 3.5% of the adolescents. Around 62% of the adolescents were normally nourished, and 38% were malnourished.Conclusions: Socioeconomic status, occupation of mothers, family types and diet of the adolescents had a significant association with poor nutritional status. It is important to understand the need for evaluation of malnourished adolescent females and their causes to prevent chronic illness and death among them.
RÉSUMÉ
This school based cross sectional study was done to estimate the prevalence of prehypertension and hypertension among apparently healthy school children in urban and rural Mysore. Prevalence of prehypertension and hypertension was 2.9% and 2.8% in urban children and 2.8% and 2% in rural children with no statistically significant difference between them.
RÉSUMÉ
school children in Mysore city. Design: Cross sectional study. Settings: Children aged 5-10 years from three schools in Mysore city were included. Study was done over a period of 1 year during 2006-2007. Participants: 726 children (59.8% males). Main Outcome: Prevalence of prediabetes. Prediabetes was defined as fasting blood sugar level between 100-125 mg/dL. Results: The prevalence of prediabetes was 3.7%. No statistically significant association was observed with major risk factors of diabetes. Conclusions: Efforts must be made to recognize type 2 diabetes in the asymptomatic prediabetes state.