[ effect of foot reflex zone therapy on the intensity of premenstrual syndrome symptoms in students of girls hostels of Tehran University of Medical Sciences, 2010]

Premenstrual syndrome [PMS] is a common disease in women. Because of unknown etiology of PMS, various medical treatments and clinical trials have been conducted to treat and prevent this syndrome. This research was performed to determine the effect of foot reflexology [reflex zone therapy] on the physical symptoms of premenstrual in students of girls hostels of Tehran University of Medical Sciences. This single blind randomized controlled clinical trial was carried out on 120 students with PMS history. After confirming the PMS, through registry of daily status [Dickerson questionnaires] in two menstruation cycles, the subjects were randomly divided into two groups of actual and false zone therapy. Actual group received 30 minutes of the treatment once per week for 8 subsequent weeks. Data were analyzed by Chi-square, exact fisher test and repeated measurement of ANOVA using SPSS-ver15. Decreased menstrual symptoms were observed in 25.26 percent of cases in actual reflex zone therapy and 3.8 percent of cases in false zone therapy. Based on the results and attended to this symptom's spread, the necessity of attention to reflex zone therapy, as a substitute and complement treatment, is clear

Detection of anti-platelet glycoprotein antibodies Using MAIPA method

AITP mostly occur in children accompanied by variable clinical sings including petechiae, purpura, ecchymosis and severe bleeding. This study has determined and characterized the anti-platelet glycoproteins in children with ITP. The aim of this study was to determinate anti-platelet glycoproteins [GPs] using MAIPA method. During 18 months 38 children with clinical signs of AITP were studied in Mofid children hospital. To determine anti-platelet antibodies by ELISA technique, washed O negative platelets were used as a source of platelet antigens. MAIPA method was used to detect antibodies against individual platelet membrane glycoprotein. The anti-platelet antibodies level above mean+ 3SD of control group was assumed as positive. The results indicated that the platelet count ranges was between 2×109/L and 95×109/L. 63.5 % out of 38 patients were anti-platelet antibodies positive with ELISA method. The correlation between the above patients with anti-platelet antibody positive and clinical signs was 0.4. Results for determination of antibody against platelet GPIIb/IIIa, GPIb/IX and GPIa/IIa using MAIPA method were 44%, 51% and 25% respectively. In conclusion the preference of MAIPA method is the detection of very small amount of antibody. Since MAIPA is the specific method for the detection of antibody against glycoprotein antigens, it has the advantage of differentiating immune and non-immune thrombocytopenia