Résumé
An association of unilateral pulmonary agenesis with in situ neuroblastoma of adrenal gland in a newborn having multiple congenital anomalies is being reported. Polycystic right kidney and absent left kidney, leading to severe oligohydramnios with secondary Potter's syndrome and Breech deformation sequence, were additional malformations present in our proposita.
Sujets)
Malformations multiples/anatomopathologie , Tumeurs de la surrénale/anatomopathologie , Humains , Nouveau-né , Prématuré , Nourrisson très faible poids naissance , Rein/malformations , Poumon/malformations , Mâle , Neuroblastome/anatomopathologieRésumé
Allantoic cysts of umbilical cord are very rare. A preterm, low birth weight, male newborn with a new constellation of anomalies, allantoic duct cysts in the umbilical cord and associated perinatally lethal malformations of VACTERL sequence, is reported. In addition, the neonate also had duodenal atresia, patent urachus, obstructive uropathy and bifid scrotum. Association of Allantoic cysts with VACTERL sequence has not been described earlier.
Sujets)
Malformations multiples/diagnostic , Duodénum/malformations , Issue fatale , Humains , Nouveau-né , Mâle , Malformations de l'appareil locomoteur/diagnostic , Scrotum/malformations , Fistule trachéo-oesophagienne/complications , Kyste ouraquien/complications , OuraqueRésumé
Acute appendicitis is rare in term neonates. In most of the reported cases, it is seen as a complication of necrotizing enterocolitis, Hirschsprung's disease, cystic fibrosis, meconium plug, inguinal hernia, umbilical hernia, Group B Streptococcal septicemia and chorioamnionitis. A surviving term male newborn with isolated acute appendicitis with perforation is reported. A high index of suspicion of acute appendicitis, early surgery and the importance of a thorough search for a perforation in cases of neonatal acute abdominal distention is stressed. Literature of this rare condition is reviewed briefly.
Sujets)
Maladie aigüe , Appendicectomie , Appendicite/diagnostic , Humains , Nouveau-né , Laparoscopie , MâleSujets)
Antibactériens , Acide acétylsalicylique/administration et posologie , Anévrysme coronarien/complications , Association de médicaments/administration et posologie , Échocardiographie , Femelle , Études de suivi , Humains , Immunoglobulines/administration et posologie , Inde , Nourrisson , Pneumopathies interstitielles/complications , Maladie de Kawasaki/complications , Radiographie thoracique , Appréciation des risques , Résultat thérapeutiqueRésumé
A case of Limb body wall complex is reported in a preterm, Low birth weight and stillborn neonate. The proposita had abdominal wall defect with evisceration of the organs into an amnio-peritonial sac, a short body stalk, torsion of spine with scoliosis and limb defects. Unusual associations present in this case were absent thymus, interstitial calcification in kidney and a history of exposure to birth control pills during first two months post-conception.
Sujets)
Muscles abdominaux/malformations , Malformations multiples , Adulte , Contraceptifs oraux , Femelle , Mort foetale , Humains , Anomalies morphologiques congénitales des membres/étiologie , Échange foetomaternel , GrossesseRésumé
Group B Streptococcus (Streptococcus agalactiae) is a well-known cause of early and late onset infections in neonates and very young infants. Recently attention has focused on the changing spectrum of invasive Group B Streptococcus (GBS) disease, including children beyond early infancy and non-pregnant adults. There is very little information available on invasive GBS infection especially meningitis in pediatric population older than three months of age. We report a case of uncomplicated meningitis due to GBS in a previously healthy 5-year-old boy. The literature on infection especially meningitis caused by Group B Streptococcus beyond infancy is reviewed.
Sujets)
Antibactériens/usage thérapeutique , Ceftriaxone/usage thérapeutique , Enfant d'âge préscolaire , Humains , Mâle , Méningite bactérienne/diagnostic , Infections à streptocoques/diagnostic , Streptococcus agalactiae/isolement et purification , Résultat thérapeutiqueRésumé
An association of Amniotic Band Disruption Sequence and Mermaid Syndrome in a newborn having multiple congenital anomalies is being reported. The newborn had aberrant string like tissues attached to the amputed fingers and toes. Adhesions of amniotic bands had disrupted the fetal parts especially anteriorly in the midline, causing multiple anomalies. Apart from these features of Amniotic Band Disruption Sequence, the newborn had complete fusion of the lower limbs by cutaneous tissue, a characteristic of Mermaid Syndrome (Sirenomelia). Associated malformations were anal stenosis, rectal atresia, small horseshoe kidney, hypoplastic urinary bladder and a bicomuate uterus. The single umbilical artery had a high origin, arising directly from the aorta just distal to the celiac axis, which is unique to sirenomelia. Theories put forward regarding the etiopathogenesis of both the conditions are discussed.
Sujets)
Malformations multiples/anatomopathologie , Maladie des brides amniotiques/anatomopathologie , Malformations crâniofaciales/anatomopathologie , Ectromélie/étiologie , Issue fatale , Femelle , Humains , Nouveau-né , Anomalies morphologiques congénitales des membres/anatomopathologie , SyndromeRésumé
A rare case of sirenomelia in a LBW, IUGR & second of a dizygotic twin having multiple congenital anomalies is being reported. Apart from the features of sirenomelia, the newborn had a single umbilical artery, radial hypoplasia, total anorectal & urogenital agenesis and undetermined sex. The single umbilical artery had a normal origin from the iliac artery. There was no Vitelline arterial steal phenomenon. Theories put forward regarding etiopathogenesis are discussed. We conclude that the anomalies in the present case are difficult to be explained with earlier proposed theories. This puts an emphasis on reconsideration of old theory of genetic injury to the embryo by unknown factors.