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Clinics ; 64(6): 535-541, June 2009. graf, tab
Article Dans Anglais | LILACS | ID: lil-517924

Résumé

OBJECTIVE: The aim of this study is to determine clinical, pathological, and treatment-relevant variables associated with long-term (90-month) overall survival in patients with lung metastases undergoing pulmonary metastasectomy. METHODS: A retrospective review was performed of patients who were admitted with lung metastases, and who underwent thoracotomy for resection, after treatment of a primary tumor. Data were collected regarding demographics, tumor features, treatment, and outcome.RESULTS: Patients (n = 529) were submitted to a total of 776 thoracotomies. Median follow-up time across all patients was 21.6 months (range: 0-192 months). The postoperative complication rate was 9.3%, and the 30-day mortality rate was 0.2%. The ninety-month overall survival rate for all patients was 30.4%. Multivariate analysis identified the number of pulmonary nodules detected on preoperative CT-scan, the number of malignant nodules resected, and complete resection as the independent prognostic factors for overall survival.CONCLUSION: These results confirm that lung metastasectomy is a safe and potentially curative procedure for patients with treated primary tumors. A select group of patients can achieve long-term survival after resection.


Sujets)
Adolescent , Adulte , Enfant , Enfant d'âge préscolaire , Femelle , Humains , Nourrisson , Nouveau-né , Mâle , Adulte d'âge moyen , Jeune adulte , Adénocarcinome/secondaire , Adénocarcinome/chirurgie , Tumeurs du poumon/secondaire , Tumeurs du poumon/chirurgie , Survie sans rechute , Estimation de Kaplan-Meier , Analyse multifactorielle , Pronostic , Études rétrospectives , Thoracotomie , Facteurs temps , Résultat thérapeutique , Jeune adulte
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