[ relationship between commanding leadership style and personality traits of nursing managers of hospitals affiliated to Tehran Medical Sciences Universities in 2014-2015]

Background: Nursing and other health care jobs will be challenged to respond the changing needs of people and changing nature society; this requires that nurses accept managerial roles to manage and support nurses' needs for continuing professional development. This study was developed to investigate the relationship between commanding leadership style and personality traits of nursing managers of hospitals affiliated to Tehran Medical Sciences Universities

Materials and methods: In this descriptive- correlational study, 140 nurse managers affiliated to hospitals of Tehran Medical Sciences Universities were selected by multi-stage sampling. The data collection tools were three standard questionnaires, including leadership style, personality traits and demographic properties. The Cronbach's alpha reliability were calculated for leadership style questionnaire as 0.86 and personality traits as 0.88. Data were analyzed by spss19 using descriptive and inferential statistics

Results: Most nurse managers had commanding leadership style and personality traits of conscientiousness There were significant inverse relationship between commanding leadership style and extraversion, openness, Adaptability and also conscientiousness personality traits [P<0.05]

Conclusion: By the personality traits score, it may be predicted leadership style of a manager's future; it is a proper way to select persons with more effective leadership style and optimization management organization

Minichromosome Maintenance-2 (MCM2) Expression Differentiates Oral Squamous Cell Carcinoma From Pre-Cancerous Lesions

Background: Proteins necessary for DNA replication and normal regulation for the cell cycle include minichromosome maintenance-2 (Mcm-2). Overexpression of this protein in several premalignant and malignant lesions has been observed. In this study, the diagnostic value of Mcm-2 expression in distinguishing histologically-proven normal oral mucosa (NOM), oral benign keratosis (OBK), oral epithelial dysplasia (OED), and oral squamous cell carcinoma (OSCC) was investigated. Materials and Methods: In this descriptive analytical study, 73 archived specimens of oral tissues, including 20 OBK, 20 OED, 20 OSCC, and 13 NOM cases were selected. The means of labeling indices (LIs) of Mcm-2 expression by immunohistochemistry in each category of lesions were calculated. The data was analyzed by one–way ANOVA, discriminant analysis, and Fisher’s exact tests. Results: The means of labeling indices (LIs) of Mcm-2 expression show statistically significant difference between the four studied groups (P<0.001). Mcm-2 had overexpression and higher positivity in OSCCs. A cut-off point of 67% was determined in order to distinguish OSCC from precancerous lesions. Conclusion: The findings indicated that Mcm-2 could be a useful marker for early detection of oral SCC and dysplasia. Also, due to the overexpression of this marker in OSCC, there exists the possibility of application of Mcm-2 for molecular target therapy in these patients.