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Osteoarthritis is a degenerative joint disease results from breakdown of cartilage that covers the ends of bones in joint. Breakdown causes bones to rub each other leading to pain, stiffness, swelling, loss of function in joint and can be accompanied by synovitis with or without joint fluid effusion. Muscle atrophy may develop if patient was inactive and did not perform exercises, which will affect functionality and stability of joint including activities of daily life. The aim of the study was to evaluate current literature and provide comprehensive overview of benefits of core muscle strengthening exercise in managing OA. The objective of this study was to discuss effectiveness of core muscle strengthening exercise in reducing pain, improving physical function, and enhancing quality of life in individuals with osteoarthritis knee. A systematic search was conducted to identify all relevant studies related to core muscle strengthening, database such as Pubmed, Cochrane library, Scopus had been used. Studies demonstrating clinical importance of core strengthening in treatment of osteoarthritis knee are limited. By performing randomized controlled trials with a big sample size, new researchers should produce more unique findings.
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To assess the significance of mulching and nutrients on the performances of Strawberry (Fragaria x ananassa) with respect to the qualitative character's during 2019–20, a field experiment was carried out at the Horticulture Research Farm-1 of the Department of Horticulture, School of Agricultural Sciences and Technology, Babasaheb Bhimrao Ambedkar University (A Central University), Vidya-Vihar, Rae Bareli Road, Lucknow. The experiment was laid out in RBD having three replications. The result revealed significantly highest Tss (11.28)0Brix, Total Sugar (8.98%), Reducing Sugar (6.41%), Non Reducing Sugar (2.57%), Acidity (0.31%) and Ascorbic Acid (41.90 mg/100g) in treatment T14 (Black polythene + Vermicompost 50% + NPK 50%) followed by the treatment T13 (Black polythene + FYM 50% + NPK 50%). Treatment T1 (the control), on the other hand, performed poorly in terms of all qualitative character’s. In light of the results, it can be said that using Black polythene with Vermicompost 50% + NPK 50% in strawberry increases all qualitative attributing characters, while Black polythene with FYM 50% + NPK 50% produced the second-best results.
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Background: Malaria is a protozoal disease caused by infection with parasites of Plasmodium species, such as P. vivax, P. falciparum, P. malariae, P. ovale and P. knowlesi through female Anopheles mosquito. Plasmodium vivax alone causes 60 to 65% of infections in India. The main objective of the study was to observe various complications in the patients affected with P. vivax malaria and to analyse the clinical, hematological and biochemical profile of these patients.Methods: A non-randomized prospective study was carried out on 170 patients with acute febrile illness admitted in the department of Medicine, SMS Hospital, Jaipur during period from October 2011 to September 2012 presented The infection was confirmed by detection of parasite (for P. vivax) in peripheral blood film by thick and thin slide methods and rapid diagnostic test (Optimal test).Results: Male preponderance was seen in the study. Death was noted in 5 (3%) patients. Thrombocytopenia (85%) was the most common finding observed. Level of serum creatinine was more than 1.5 mg/dl in 34.7% patients. Thirty-one patients (18.23%) had severe anaemia (Hb <6 gm/dl). Severe hypoglycemia was observed in 19 patients (<40-60 mg/dl). Acute renal failure was common comorbidity observed in majority of the patients. Mean LDH value was significantly higher in patients with hepatitis and anemia.Conclusions: The clinical pattern of P. vivax monoinfection has changed recently. Every patient of P. vivax malaria should be evaluated thoroughly for clinical or biochemical evidence of any complications and patients presenting with complications should managed as per guidelines of severe malaria.
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Background: Osteoporosis is commonly associated with chronic liver disease. Pathologic fracture in osteoporotic patients affects quality of life as well as decrease life expectancy. Around 40% of patients with chronic liver disease may experience osteoporotic fracture. The present study was undertaken to observe the relation of bone mineral density (BMD) with severity of liver cirrhosis along with effects of smoking and alcohol.Methods: A total of 187 liver cirrhosis patients who were admitted in SMS Hospital were taken for study and were classified into class A, B, C as per Child Turcot Pugh’s classification, after applying inclusion and exclusion criteria. All patients underwent standard laboratory testing and bone densitometric studies of the lumbar spine using dual X-ray absorptiometry (DEXA) scan. Statistical analysis done.Results: The bone mineral density was significantly low in Class C. Class C have 41 patients of osteoporosis out of 62 whereas only 16 patients have osteoporosis in Class B and only 1 case of osteoporosis in class A. Hypocalcemia and hypophosphatemia were more in class C as in comparison to class A and B. Also, chronic smoking and alcohol intake were strongly associated with the severity of cirrhosis.Conclusions: The prevalence of osteopenia and osteoporosis is higher in cirrhotic patients and significantly increases with severity. Hypocalcemia and hypophosphatemia are also associated with the cirrhosis. Thus, patients should undergo routine bone densitometry assessment and, if necessary, to be treated for osteoporosis
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Background: Psychotropic drugs have had a remarkable impact in psychiatric practice. The continuous monitoring of prescription and drug utilization studies may help to identify the problem involved in therapeutic decision and promote rational prescribing. Very few studies from India have evaluated the prescription pattern of Psychiatrists. Present study was undertaken to analyze the prescription pattern and drug used in psychiatric Out Patients of private practitioners of Central India. Methods: One thousand prescriptions were collected by undergraduate students from chemist and analysed. Study parameter like demographic profile of patients viz. age, sex, diagnosis were recorded. Basic drug indicators, the prescribing pattern of antipsychotics and other categories of drugs were also recorded. The most common and, top brands of anti psychotics were analyzed .Inappropriate prescription if any were recorded and analyzed further. Result: The most common psychotropic drugs were anti-anxiety in 361(36.1%) and antidepressants 130 (13%) prescribed for various psychiatric disorder. Usage of Sedative Hypnotics 104(10.4%), anti-psychotics 90(9%) and anticonvulsants 80 (8%) drugs in prescriptions. The incidence of polypharmacy (22%) was common occurrence in prescriptions. The commonest combination prescribed was of tricyclic antidepressant with benzodiazepines. Central anti-cholinergic was commonly prescribed with anti psychotics. Conclusions: Anti-anxiety drug (benzodiazepines) was the most frequently prescribed class of psychotropic drugs in various psychiatry disorders. The prescribing prevalence of Alprazolam with different brand names was more than that of other benzodiazepines. The combination of different psychotropic drugs were also prescribed.
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High severity of Alternaria blight disease is a major constraint in production of rapeseed-mustard in India. The aim of this study was to investigate the suppressive potential of chemicals viz., zinc sulphate, borax, sulphur, potash and calcium sulphate, aqueous extracts viz., Eucalyptus globosus (50 g l-1) leaf extract and garlic (Allium sativum) bulb (20 g l-1) extract, cow urine and bio-agents Trichoderma harzianum, Pseudomonas fluorescence in comparison with the recommended chemical fungicide (mancozeb), against foliar disease Alternaria blight of Indian mustard [Brassica juncea (L.) Czern. and Coss] under five different geographical locations of India. Mancozeb recorded the lowest mean severity (leaf: 33.1%; pod: 26.3%) of Alternaria blight with efficacy of garlic bulb extract alone (leaf = 34.4%; pod = 27.3%) or in combination with cow urine (leaf = 34.2%; pod = 28.6%) being statistically at par with the recommended chemical fungicide. Chemicals also proved effective in reducing Alternaria blight severity on leaves and pods of Indian mustard (leaf = 36.3- 37.9%; pod = 27.5-30.1%). The effective treatments besides providing significant reduction in disease severity also enabled increase in dry seed yield of the crop (mancozeb = 2052 kg ha-1; garlic = 2006 kg ha-1; control = 1561 kg ha-1).
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The association of juvenile rheumatoid arthritis and type 1 diabetes mellitus is rare. These two diseases belong to different clusters of autoimmune diseases and it is uncommon for diseases belonging to different cluster occurring together. This is a case report of a fourteen-year-old girl having the above two disorders along with autoimmune thyroid disease.