Your browser doesn't support javascript.
loading
Montrer: 20 | 50 | 100
Résultats 1 - 1 de 1
Filtre
1.
Asia Pacific Allergy ; (4): 74-81, 2017.
Article Dans Anglais | WPRIM | ID: wpr-750099

Résumé

BACKGROUND: Epidemiological studies show that immunoglobulin E (IgE) levels were higher in subjects with acute coronary events. However, it is unknown if the increased IgE level is a marker of future coronary incidents and whether it may be regarded as a risk factor of an ischemic heart disease. OBJECTIVE: Our aim was to investigate the relationship between IgE levels and some atherosclerotic markers in patients without known atherosclerotic disease. METHODS: Fifty patients (mean age, 40.96 ± 10.8 years) with high serum IgE levels due to various conditions who did not display evidence of an atherosclerotic disease and 30 healthy control subjects (mean age, 47 ± 8.27 years) were included in the study. Atherosclerotic disease markers including adhesion molecules like vascular cell adhesion molecule-1, intercellular adhesion molecule-1, proinflammatory cytokines such as interleukin-6, endothelin-1, and systemic inflammatory markers such as high sensitivity C-reactive protein were determined by enzyme-linked immunosorbent assay (ELISA). Endothelial functions of the coronary arteries were determined by coronary flow reserve (CFR) measurements and carotid intima media thickness using transthoracic Doppler echocardiography.


Sujets)
Humains , Athérosclérose , Protéine C-réactive , Épaisseur intima-média carotidienne , Vaisseaux coronaires , Cytokines , Échocardiographie-doppler , Endothéline-1 , Test ELISA , Études épidémiologiques , Immunoglobuline E , Immunoglobulines , Molécule-1 d'adhérence intercellulaire , Interleukine-6 , Ischémie myocardique , Anatomopathologie , Facteurs de risque , Molécule-1 d'adhérence des cellules vasculaires
SÉLECTION CITATIONS
Détails de la recherche