Résumé
The effects of indomethacin-prednisolone on urinary bladder carcinoma was investigated All patients underwent full clinical evaluation including cystoscopy and clinical staging of the tumour. The mean tumour diameter was determined and a biopsy material was obtained. Patients were instructed to take prednisolone 15 mg/day orally and indomethacin 200mg/day rectally for four weeks. At the end of treatment, the intravenous urogram and cystoscopy were repeated. Nine patients had completed the study. A significant reduction [P < 0.05] in the mean tumour diameter was observed. Furthermore, a tendency for symptomatic and radiological improvement was noted. It is concluded that indomethacin-prednisolone combination has a beneficial effect on carcinoma of the bladder