1.
Bulletin of Faculty of Pharmacy-Cairo University. 1998; 36 (3): 141-5
Dans Anglais
| IMEMR
| ID: emr-47809
Résumé
The purpose of the present study was to investigate the effect of fluorine atom on certain pharmaceutical properties of flufenamic acid [F] using mefenamic acid [M] as a control. Both drugs have been anthranilic acid derivatives with 3 fluorine atoms in the former. The pharmaceutical properties studied were flowability [angle of repose], bulk density, porosity, and wettability [sinking time]. Dissolution and release studies of both drugs from capsules and ointment bases were also carried out