Role guided intraperitoneal port-a-cath insertion in the managment of cancer ovary of fluoroscopic

The use of intraperitoneal [IP] chemotherapy as a treatment for ovarian cancer has been demonstrated to result in improved survival. The aim of this work is to evaluate the applicability and efficacy of fluoroscopic placed intraperitoneal port-A-cath and to assess the response rate to intraperitoneal chemotherapy in cases of ovarian carcinoma. The studied group included, 22 female patients with malignant ovarian cancer whom referred from gynecological surgery and gynecological oncology units to the Vascular and Interventional Radiology Unit, Ain Shams University Hospitals, for peritoneal port-A-cath application. All the patients were known cases of either primary or recurrent ovarian cancer, underwent cytoreductive surgery and referred to us. Intraperitoneal port-A-cath with the aid of fluoroscopy showed highest technical success [91.9%] and lowest complication rate on the long run compared to other methods of peritoneal access. Patients with cancer ovary showed significant improvement of the disease process denoted by changes in the degree of ascites, peritoneal nodules and tumor marker level after receiving combined IV/ IP chemotherapy. Port catheters proved to be the most safe method of long term access to the peritoneal cavity with the lowest complication rate compared to other methods of access to the peritoneal cavity

Value of ultrasonographic and colour coded doppler parameters in diagnosis of hepatitis C related chronic liver diseases, correlation with pathological diagnosis

Liver biopsy is the gold standard for assessment of fibrosis and necroinflammatory changes in chronic hepatitis and cirrhosis. However, the use of biopsy in clinical practice has some limitations related to sample errors and possible complications. Ultrasonography has become the most common and valuable method for assessment of liver disease because of its low cost, easy performance and high acceptability by the patients. It could provide not only valuable information on the morphological changes of the liver but also liver hemodynamics by Colour Doppler flow imaging. To evaluate the relationship between abdominal ultrasonography and selected colour Doppler parameters on one hand and the liver histopathology on the other hand, in patients with Hepatitis C related chronic liver disease. The study was performed on 2 groups: Group [1]: Included 40 patients who presented with Hepatitis C virus [HCV] related chronic liver disease, diagnosed by clinical assessment, biochemical profile, hepatitis markers and liver biopsy. Group [2]: Included 20 healthy subjects as a control group. Both groups were subjected to history taking, full clinical examination and laboratory work up. Abdominal ultrasonography and colour Doppler imaging were done with special emphasis on certain parameters. Among ultrasonographic parameters, there was a high statistical significance for the largest oblique diameter of the right hepatic lobe, GB wall thickness, hepatic parenchymal echopattern together with a functional score formed of serum albumin, bilirubin and TNR to predict the degree of hepatitis inflammation among group 1. The studied Doppler parameters [phasicity of hepatic veins, main portal vein trunk, congestive index of the PV, hepatic artery diameter hepatic artery resistive index, splenic artery diameter and splenic vein diameter] when combined with the functional score could significantly predict the degree of hepatitis inflammation. Ultrasonography and Doppler studies can predict the changes in the liver biopsy but their validity is increased when combined with a functional assessment of the liver condition