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We reported an unusual case of choroidal melano-cytoma who was enucleated with diagnosis of retinoblastoma. A 14-month-old boy has been referred to the clinic with compliant of left eye exodeviation for about 10 months. Ocular examination and imaging work-up revealed retinal detachment with a calcified lesion. The patient underwent enucleation of the affected eye with diagnosis of retinoblastoma. Histopathological findings indicated large, polyhedral shape cells of the tumor with small nuclei and abundant cytoplasm filled with melanin granules, suggesting diagnosis of melanocytoma of the choroids and ciliary body. Many cases of the simulation of the malignant melanoma of the choroids and ciliary body with melanocytoma has been reported previously, but melanocytoma resembling as a calcified lesion and retinal detachment with diagnosis of retinoblastoma is a rare condition which has not been reported anywhere.
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·We report clinical manifestations,angiographic,and optical coherence tomography (OCT) findings of four cases with bilateral idiopathic cystoid rnacular edema (CME).All were male with age between 30 and 52 years.All of them had compliant of bilateral visual loss during the last week.Fundus examination of their eyes showed macular edema in the posterior pole bilaterally. Fluorescein angiography revealed no specific finding in one of them and "typical petaloid pattern" in others.OCT showed subretinal fluid in all of them.All patients were managed with diagnosis of idiopathic CME,and after 6 weeks they had improved visual acuity.
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AIM:TO evaluate chromosome 8 abnormalities in Duane's retraction syndrome(DRS)type 1.METHODS:We evaluated chromosome 8 abnormalities in 29 consecutive cases of DRS type Ⅰ.DNA was isolated from the peripheral leukocytes of patients using a genomic DNA extraction kit,then D8S553 and D8S1797 markers used for polymerase chain reaction(PCR).RESULTS:None of the cases were positive for the two markers D8S553 and D8S1797 on chromosome 8 which were tested in our study.CONCLUSION:The possible cause of this finding is that DRS in our patients is more commonly sporadic rather than familial.We recommend study with more cases,other markers,and different chromosomes.
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AIM: To review the characteristics, complications, and epidemiology of perforating eye injury treated at a referral eye centre in Tehran, over one year, ·METHODS: The medical records of 959 patients hospitalized in Farabi Eye Hospital, Tehran, Iran, due to ocular trauma in 2002 were studied. Information recorded included demographic information (age, sex, and occupation), offending agent, type of trauma, initial visual acuity, location where trauma occurred, accompanying signs and symptoms, and types of treatment provided. ·RESULTS: Mean age of patients was (22.6±16.4) years with a peak age of 21-25 years in males and under 5 years in females. The ratio of male to female was 4.2:1.62.4% of patients had penetrating trauma, 33.9% had blunt trauma, and 3.7% had mixed or chemical trauma. Metallic agents were the most common cause of penetrating ocular trauma, while stone was the most common blunt counterpart. Foreign bodies were observed in 23.4% of cases. Cornea was the most com-mon site of rupture (46.7%). ·CONCLUSION: Based on this study, penetrating trauma is more common than blunt trauma. Younger individuals are more prone to ocular trauma. Cornea is the most common site of injury.
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· We report successful treatment of a case of fungal keratitis caused by Pseudallescheria boydii with minimal corneal scar. A 71-year-old woman with history of pain, redness and foreign body sensation presented to our tertiary eye center. Initial corneal scraping revealed fungal elements. After two days fungal culture became positive, and after five days it was shown to be growth of Pseudallescheria boydii. The patient achieved clinical cures with medical therapy alone with minimal corneal scar and good visual outcome of 3/10.
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·AIM: To evaluate the efficacy of standard and undercorrected surgical methods in patients with partially accommodative esotropia (PAET).·METHODS: Twenty-five patients with PAET and normal accommodative convergence/accommodation ( AC/A )were divided into two groups for alternate surgical plan including standard method (13 patients) and under-corrected method (12 patients) in a randomized fashion.Standard method is based on measured deviation through full hyperopic correction at distant target and was performed by Parks scheme. Undercorrected method criteria is 20% lower than standard. All patients underwent symmetrical bilateral medial rectus recessions (BMR), and all of them were followed for 6 months.·RESULTS: Six months after operation, surgical success (defined as tropia =s 8A at distant and near fixation through full hyperopic correction) was 46% in standard group and 91% in undercorrected group. Overcorrection were observed 54% in standard group and 9% in undercorrected group (P＜0.05). There was no residual esotropia. There was no correlation between surgical success rate or overcorrection rate and age, mean of preoperative spherical equivalent or preoperative eye deviation.·CONCLUSION: Undercorrected BMR surgery has a lower overcorrection rate and higher surgical success rate than standard surgery in patients with PAET and normal AC/A.
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AIM: To evaluate correlation of retinopathy and diabetic peripheral neuropathy (DPN) as microvascular complications of diabetes and also to identify their risk factors in patients with type 2 diabetes.MEHTODS: We conducted a cross-sectional study in an outpatient diabetes clinic during an 18-month period. 100 patients (51 male and 49 female), all affected by non-insulin-dependent diabetes mellitus (NIDDM), were examined for the presence of diabetic neuropathy and diabetic retinopathy.RESULTS: 78.1% of patients with retinopathy had DPN; and 79.1% of patients with DPN had retinopathy. Analysis of the association between DPN and retinopathy showed no significant correlation between them. 90.9% of patients with proliferative diabetic retinopathy (PDR) had DPN; and 27.8 %of patients with DPN had PDR. Both the univariate analysis and multiple logistic regression analysis revealed significant correlation between them (r =0.42, P =0.02).CONCLUSION: A severe diabetic retinopathy is associated with diabetic neuropathy. Our study further supports that diabetic neuropathy might be used as a tell-tale sign of diabetic retinopathy, necessitating more intensive ophthalmic care, especially in long-lasting diabetes.
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ATM:To determine the tearing angle and tearing force,and effects of associated pressures in tearing of various materials and human lens capsule in continuous curvilinear capsulorhexis(CCC).METHODS:Tearing was done on different materials such as aluminum Iaminated paper,different types of thin transplant plastics and human Iens capsule with blunt tip needle.During the procedure,angle and direction of force were measured.Effects of increased underlying pressure on tearing of tearable materials and effect of anterior chamber depth and vitreous pressure on 24 postmortem hunlan eyes with different ages (range from10 to 75 years),was evaluated.RESULTS:Tearing angle in every material was unique for that material.Angle and force of tearing was decreased reversely with increasing age (from 85 degree in a 10-years-old to 10 degree in older than 50 years).Increasing vitreous pressure and decrease in AC depth causes higher pressure on point of tearing.Safe methods in controlling CCC are discussed jn the context.OONCLUSION:Understanding the physics and vector of forces during CCC is necessary in good performance and avoidance of radial tears.Onange in capsular properties between difierent ages and different type of cataract causes different tearing angle and tearing force that should be considered during CCC.
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· AIM: We describe visual improvement after phacoemulsification with intraocular lens (IOL) implantation in 7 eyes with anterior lenticonus secondary to Alport syndrome.· METHODS: 7 eyes from 4 patients with Alport syndrome underwent phacoemulsification with IOL implantation due to anterior lenticonus.· RESULTS: All of the patients resumed excellent visual acuity after surgery.· CONCLUSION: We recommend the phacoemulsification with IOL implantation as a safe procedure in anterior lenticonus due to Alport syndrome.