Psoriasis and indigo naturalis as a treatment

Psoriasis is an inflammatory and proliferative disease. Psoriasis clinical features vary from plaque-type psoriasis to pustular form. Psoriasis is an immune-mediated disease, which affects epidermal keratinocytes. Regard to serious side effects of chemical therapy in psoriasis patients, various projects were performed all around the world to find new therapeutic approaches for psoriasis. Various studies confirmed that Indigo naturalis treatment induced long-term remission in patients with psoriasis in all ages

High Levels of Anti-Heat Shock Protein 27 Antibody in Pemphigus Vulgaris

No abstract available.

[Goltz syndrome with absence of fibula]

Goltz syndrome [Focal Dermal Hypoplasia] is a rare syndrome results from developmental defects in tissues with meso-ectodermal origin such as skin, eyes, mouth and teeth, musculoskeletal and central nervous system. We report a 6 years old girl with FDH who had several features of skin, eyes and mouth involvement with multiple skeletal defects and absence of fibula which has not been reported previously

Basal cell nevus syndrome presenting as a tender mass of the jaw: a case report

Basal cell nevus syndrome [Gorlin's syndrome] is a rare autosomal dominant tumor-predisposing syndrome which is classically consisted of multiple cutancous basal cell carcinomas, odontogenic keratocysts of the jaw, pits of the palms and soles, ectopic calcification of cranial membranes and various skeletal abnormalities. We report a typical case of Gorlin's syndrome in a 50-year-old man who presented with a tender mass of jaw

[Specific cutaneous manifestations in adult Tcell leukemia/lymphoma]

Adult T cell leukemia/lymphoma [ATLL] is an aggresive malignancy which may occur in human T lymphotropic virus [HTLVl] infected persons. HTLV1 is endemic in Khorasan with prevalence of 2.3% in general population. Since specific cutaneous manifestations of lymphoma may occur in a significant number of patients, we studied ATLL patients in Mashhad In this descriptive study the demographic and clinical data of 23 patient suffering from ATLL who were admitted in hematology and dermatology departments of Ghaem Hospital, during 1995-2004 and had specific cutaneous lesions confirmed histopathologically with atypical lymphocytes in skin lesions, were recorded and analyzed. Eleven patients were male and 12 were female. The mean age of patients was 48.17 +/- 14.1 years. Birth places of over 85% of cases were north of Khorasan. The most common types of specific skin lesions were maculopapular rash in 11 cases [47.8%] and papular lesions in 4 cases [17.4%]. Other lesions included plaque, icthyosis like, erythroderma, tumor, and nodular lesions. In most of patients [56.5%] the skin lesions were generalized The most common type of specific skin lesions in ATLL was maculopapular rash especially with generalized distribution. Other types of specific skin lesions in order of frequency were papule, plaque, icthyosis like, nodule, tumor and erythroderma

Survery of cutaneous complications after renal transplantation in Emam Reza [PH] and Qaem Hospitals, Mashhad

Renal transplantation is an appropriate treatment for end stage renal disease and helps prolongation of patients survival with better quality, but immunosuppressive drugs that are used for inhibition of rejection after transplantation may cause some adverse effects in other organs such as the skin. Apparently, early recognition of those side effects and their appropriate management can reduce morbidity and mortality. This study was designed to study cutaneous complications in renal transplantation recipients. In this descriptive study cutaneous side effects in one hundred kidney transplant patients who were admitted to transplantation clinics of Qaem and Emam Reza hospital of Mashhad during a six-month period [April to September 2003] were studied. Sixty-five patients were males and 35 cases were females. The mean age was 36 years [SD=14]. Totally, cutaneous manifestations were observed in 88% of patients. In a descending order they included hypertrichosis, cushinoid appearance, gingival hyperplasia, steroid acne, common warts, herpes simplex infection, superficial fungal infection, candidiasis, actinic keratosis, porokeratosis, lymphoma, stria, telangiectasia and sebaceous hyperplasia. Early recognition of these complications and appropriate treatment of them can reduce probable mortality and morbidity