Xeroderma pigmentosa - squamous cell carcinoma lip

A 10 Years old female patient of xeroderma pigmentosa [XP] presented with an oval shaped swelling on left upper lip for 2 months. Excisional biopsy was done and histopathology revealed moderately differentiated Squamous cell carcinoma. We report this case as Xeroderma pigmentosa with squamous cell carcinoma is rarely seen in ENT practice

Ossicular damage in chronic suppurative otitis media- study of 100 cases

To identify the extent of ossicular chain damage in chronic suppurative otitis media [CSOM]. Prospective study. This study was conducted at department of Otolaryngology-Head and Neck Surgery, Dow Medical College and Civil Hospital, Karachi. March 2003 to March 2004. 100 cases presenting with CSOM under going mastoid exploration. The age of presenting of CSOM undergoing mastoid exploration ranged from 5 yrs to 55 yrs. The most commonly affected group was between 11 yrs to 20 yrs [50%]. Females were affected more than male [60%]. All patients presented with chronic discharging ears having conductive deafness, 60% presenting with moderate degree of hearing impairment [31 to 50 dB] while 30% had less than 30 dB loss and only 10% had greater than 50 dB loss. Granulation tissue was found in 47 cases, cholesteatoma in only 30 cases, inflamed mucosa in 24 cases, polyps in 7 cases and tympanosclerosis in 3 cases. Handle of malleus was necrosed in 30 cases, while in 20 cases all the three ossicles were necrosed except the foot plate of stapes. Long process of incus and handle of malleus were missing in 10 cases and the long process of incus alone was necrosed in 5 cases while malleus and incus were missing in 5 cases. In 30 cases all the ossicles were intact and mobile. Multi ossicular chain damage is more frequent than single ossicle damage in cases of chronic discharging ears. It is also observed that cholesteatoma is less frequent than the granulation tissue and inflamed mucosa in our setup