Antibiotic Sensitivity and Clinico- epidemiological Profile of Staphylococcal Infections.

This hospital-based study describes the antibiotic sensitivity of 66 S. aureus isolates from the admitted children (age 0-18 y) in a tertiary hospital of Kolkata, India. Methicillin-resistant S. aureus constituted 16.7% (n=11) of the isolates. Clindamycin-resistance was observed in 60% and 82% of methicillin-sensitive and methicillin-resistant strains, respectively.

Macrophage Activation Syndrome in Kawasaki Disease.

Background: Kawasaki disease is an acute febrile vasculitis of childhood. Macrophage activation syndrome is a rare life threatening complication. Case characteristics: 4-yearold boy with Kawasaki Disease treated with intravenous immunoglobulins. Observation: He developed encephalopathy, hepatosplenomegaly and pancytopenia. Blood investigations and bone marrow aspiration suggested macrophage activation syndrome. Outcome: Good response to pulse methylprednisolone (30 mg/kg/d) for 5 days. Message: Macrophage activation syndrome may complicate Kawasaki disease.