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1.
Indian J Ophthalmol ; 2010 Jan; 58(1): 64-66
Article Dans Anglais | IMSEAR | ID: sea-136016

Résumé

We report an interesting ocular finding of bilateral multiple coin-shaped epithelial lesions along with the confocal microscopy findings in a patient following an acute attack of erythema multiforme (EM) minor. A 30-year-old male presented with a history of watering and irritation in both eyes of three days duration. He was diagnosed to have EM minor and was on oral acyclovir. Slit-lamp examination revealed multiple coin-shaped epithelial lesions. Confocal microscopy showed a corresponding conglomerate of hyper-reflective epithelial lesions. The corneal lesions resolved over six weeks with oral steroids and acyclovir. An immunological mechanism is suspected.


Sujets)
Maladie aigüe , Adulte , Antiviraux/usage thérapeutique , Cornée/anatomopathologie , Maladies de la cornée/traitement médicamenteux , Maladies de la cornée/étiologie , Maladies de la cornée/anatomopathologie , Diagnostic différentiel , Association de médicaments , Études de suivi , Glucocorticoïdes/usage thérapeutique , Humains , Mâle , Microscopie confocale/méthodes , Syndrome de Stevens-Johnson/complications , Syndrome de Stevens-Johnson/diagnostic , Syndrome de Stevens-Johnson/traitement médicamenteux
2.
Indian J Ophthalmol ; 2009 Mar-Apr; 57(2): 127-32
Article Dans Anglais | IMSEAR | ID: sea-70224

Résumé

BACKGROUND: Endoscopic cyclophotocoagulation (ECP) is a relatively new method of cyclodestruction which can be used in the management of refractory glaucomas. AIM: To evaluate the safety and efficacy of ECP in the management of refractory glaucomas. SETTINGS AND DESIGN: Prospective interventional non-comparative study. MATERIALS AND METHODS: Fifty eyes of 50 patients with refractory glaucoma, whose intraocular pressures (IOP) were not under control with maximal medical therapy underwent ECP, by the anterior, or pars plana route. IOP, best corrected visual acuity (BCVA), and the number of anti-glaucoma medications, were compared postoperatively to preoperative values. Success was defined as IOP pound 22 mmhg, with or without use of medications. STATISTICAL ANALYSIS USED: Student's t test and repeated measures ANOVA were used to evaluate change in IOP and Student's t test, for comparison of BCVA. Kaplan Meier survival curve was plotted. Wilcoxon signed rank test was used to evaluate reduction in medications. RESULTS: Patients were followed for an average of 12.27 months (3-21months). IOP decreased significantly from 32.58 +/- 9.16 mmHg to 13.96 +/- 7.71 mmHg at last follow-up ( P < 0.001, student's t test). BCVA was significantly improved in the postoperative period ( P < 0.001, student's t test). The average number of antiglaucoma medications decreased from 2.51 +/- 0.97 to 1.09 +/- 1.16 ( P < 0.001, Wilcoxon signed rank test). ECP had a success rate of 82.2%. CONCLUSION: Endoscopic cyclophotocoagulation is an effective procedure in this subset of refractory glaucomas.


Sujets)
Antihypertenseurs/administration et posologie , Corps ciliaire/chirurgie , Endoscopie , Femelle , Glaucome/chirurgie , Humains , Pression intraoculaire/physiologie , Coagulation par laser/méthodes , Mâle , Adulte d'âge moyen , Études prospectives , Résultat thérapeutique , Acuité visuelle/physiologie
3.
Indian J Ophthalmol ; 2007 Sep-Oct; 55(5): 376-8
Article Dans Anglais | IMSEAR | ID: sea-69749

Résumé

Posterior polymorphous dystrophy is a rare corneal dystrophy, usually detected by chance. This case series describes the morphologic features in the three different types of posterior polymorphous dystrophy using confocal microscopy.


Sujets)
Adulte , Sujet âgé , Maladies de la cornée/anatomopathologie , Dystrophies héréditaires de la cornée , Stroma de la cornée/innervation , Diagnostic différentiel , Endothélium de la cornée/anatomopathologie , Femelle , Humains , Mâle , Microscopie confocale , Adulte d'âge moyen
4.
Article Dans Anglais | IMSEAR | ID: sea-91683

Résumé

A 42-year-old man diagnosed to be HIV positive and on highly active antiretroviral treatment (HAART), presented with double vision and gradual drooping of the left eyelid. He had left 3rd cranial nerve palsy and partial right lower-motor-neuron facial palsy. CT of the PNS revealed soft tissue filling the right maxillary sinus antruin. Further workup showed the mass to be an NK/T cell lymphoma.


Sujets)
Adulte , Thérapie antirétrovirale hautement active , Cécité/étiologie , Infections à VIH/complications , Humains , Cellules tueuses naturelles , Lymphome lié au SIDA/diagnostic , Lymphome T/diagnostic , Mâle , Tumeurs du nez/diagnostic
5.
J Postgrad Med ; 2000 Oct-Dec; 46(4): 251-2
Article Dans Anglais | IMSEAR | ID: sea-115943
7.
Indian J Exp Biol ; 1998 Jan; 36(1): 16-21
Article Dans Anglais | IMSEAR | ID: sea-62900

Résumé

Acute myocarditis was induced in dogs and rabbits by injection of scorpion (M. tamulus concanesis, earlier called Buthus tamulus) venom by s.c., i.m. or i.v. routes. A decrease in thyroxine (T4) levels was observed following i.v. injection of venom in dogs. In rabbits the venom (i.m.) did not elicit any change in T4 levels. Envenomation (s.c.) resulted in a reduction in triiodothyronine (T3) levels in dogs. Venom injection (s.c.) along with i.v. administration of the species specific antivenom (AScVS) did not cause any change in T3 and T4 levels in general. However an increase in T3 levels following AScVS was observed in envenomated dogs. The results suggest that scorpion envenomation caused an autonomic storm releasing massive amounts of catecholamines, angiotensin II, suppressed insulin secretion and reduced circulating T4 and T3 levels. Decrease in thyroid hormones results in fall in body temperature. Changes in the body temperature may increase the sensitivity of the scorpion venom and influence the course of toxicity.


Sujets)
Animaux , Sérums antivenimeux/usage thérapeutique , Chiens , Électrocardiographie , Femelle , Mâle , Myocardite/sang , Lapins , Venins de scorpion/administration et posologie , Spécificité d'espèce , Thyroxine/sang , Tri-iodothyronine/sang
8.
Indian J Ophthalmol ; 1995 Dec; 43(4): 181-4
Article Dans Anglais | IMSEAR | ID: sea-69873

Résumé

Hundred and thirty patients, aged above 40 years, with senile cataract were examined. Age and colour were selected as the probable preoperative indicators of nuclear hardness. The lens material collected after manual extracapsular extraction was washed and the nucleus isolated. The diameter and central thickness of the nucleus were measured; the mean diameter and mean central thickness were 7.13 mm +/- 0.76 and 3.05 mm +/- 0.48, respectively. The hardness of the nucleus was measured with a lens guillotine designed by us. Regression analysis was applied to the parameters measured and these were compared with the colour and age. The parameters measured had the following relationship: Colour vs hardness (r value = 0.7569) (p < 0.001) Colour vs diameter (r value = 0.3962) (p < 0.001) Colour vs central thickness (r value = 0.4785) (p < 0.001) Age vs hardness (r value = -0.0499) (p > 0.05) Age vs diameter (r value = 0.0987) (p > 0.05) Age vs central thickness (r value = 0.1700) (p > 0.05) The values showed that colour had a statistically significant relationship with all the 3 parameters (p < 0.001), while age had no significant relationship with the same parameters. The results indicated that colour can be used more reliably to predict physical characteristics of the cataractous lens nucleus, the preoperative knowledge of which would help the surgeon in planning small-incision surgery including phacoemulsification.


Sujets)
Adulte , Facteurs âges , Sujet âgé , Cataracte/anatomopathologie , Extraction de cataracte , Couleur , Femelle , Dureté , Humains , Inde , Noyau du cristallin/anatomopathologie , Mâle , Adulte d'âge moyen
11.
Indian J Ophthalmol ; 1992 Jan-Mar; 40(1): 9-10
Article Dans Anglais | IMSEAR | ID: sea-72101

Résumé

Eighty patients with allergic conjunctivitis were treated with immunotherapy employing specific allergens. Sixty-two percent of these showed beneficial response. In cases of vernal conjunctivitis needing topical steroid preparations frequently for control of symptoms, immunotherapy is worth attempting to cause remission of symptoms.


Sujets)
Adolescent , Adulte , Enfant , Enfant d'âge préscolaire , Conjonctivite allergique/thérapie , Désensibilisation immunologique , Femelle , Humains , Mâle
12.
Indian J Ophthalmol ; 1989 Apr-Jun; 37(2): 58
Article Dans Anglais | IMSEAR | ID: sea-71076
13.
Indian J Exp Biol ; 1989 Mar; 27(3): 242-4
Article Dans Anglais | IMSEAR | ID: sea-62842

Résumé

Crude venom (4 mg/kg) of scorpion (B. tamulus) was given in saline to anaesthetized dogs and rabbits. It produced a reduction in gastric H+ ion concentration in dogs with acute myocarditis. Simultaneously an increase in circulating amylase and lipase level was also observed. However 60% venom poisoned rabbits showed an elevated lipase level without a parallel increase in amylase. It is suggested that the venom acts directly on exocrine pancreas to cause acute pancreatitis.


Sujets)
Maladie aigüe , Animaux , Chiens , Femelle , Suc gastrique/métabolisme , Concentration en ions d'hydrogène , Mâle , Myocardite/induit chimiquement , Pancréatite/induit chimiquement , Lapins , Venins de scorpion/toxicité , Scorpions
16.
Bull Indian Inst Hist Med Hyderabad ; 1987 ; 17(2): 89-93
Article Dans Anglais | IMSEAR | ID: sea-1875
18.
Indian J Ophthalmol ; 1987 ; 35(5-6): 271-3
Article Dans Anglais | IMSEAR | ID: sea-72630
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