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Gamme d'année
1.
EMHJ-Eastern Mediterranean Health Journal. 2004; 10 (4-5): 627-632
de Anglais | IMEMR | ID: emr-158330

RÉSUMÉ

Antiphospholipid antibodies may play and important role in the pathogenesis of retinal vascular occlusions; investigated the prevalence among 33 patients with retinal vein and artery occlusions and 80 controls. Prevalence was 33% and 5% respectively. Ophthalmic examination and fluorescein angiography showed that occlusions were due to ischaemic events. The 11 patients were diagnosed with antiphospholipid syndrome: 9 patients were treated successfully with laser photocoagulation and anticoagulant and anti-aggregant therapy. Two patients with antiphospholipid antibodies associated with resistance to activated protein C had unfavourable outcomes. Our results suggest a correlation between antiphospholipid syndrome and retinal vein occlusions; we recommend a systematic search for antiphospholipid antibodies in occlusions of unexplained origin and laser photocoagulation treatment and long-term oral anticoagulant and anti-aggregant therapy


Sujet(s)
Adulte , Sujet âgé , Femelle , Humains , Mâle , Adulte d'âge moyen , Administration par voie orale , Anticorps antiphospholipides/sang , Anticoagulants , Études cas-témoins , Loi du khi-deux , Angiographie fluorescéinique , Coagulation par laser , Occlusion veineuse rétinienne/étiologie
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