Résumé
Growth improvement on L-Garnitine therapy has been observed in transfusion dependent sickle cell anaemia patients. We plan to study 27 Egyptian sickle Jell patients on low transfusion regimen for 6 months follow-up study period. The study included .13 males and 14 females aged [546 years]. Anthropometric measurements were done before starting L-Carnitine and six months after L-Carnitine [50 mg/kg orally]. Measurements included weighs, height, body mass index, skeletal muscle development and measurements of body fat. Twenty patients [10 males and 10 females.] of the same age and social classes were followed in the study as a control. Patients were divided according to their ages into 2 groups [5-10 years] and [11-26 years,]. The study showed increase in the standard deviation score [SDS] of weight and height per age of the supplemented children compared to control groups. There were increase in the chest/head ratio [C/H R], deltoid circumference, mid arm muscle circumference, mid arm fat circumference and subscapaular and supra iliac skin fold thicknesses compared to controls. These results were more apparent in the young age groups. We concluded the beneficial effect of L-Carnitine on the physical growth of patients with sickle cell anaemia especially the young, a longer period of supplementation is recommended