Résumé
The objective of this study was to prove the causal association of Helicobacter pylori infection and the development of GERD in order to be able to plan a program for intervention. The work was conducted on 30 patients suffering from symptoms suggestive of gastroesophageal reflux disease diagnosed by upper endoscopic examination and 20 matched controls were chosen complaining from dyspeptic symptoms, but were completely normal by upper endoscopic examination. The patients and controls were selected from Mataria Teaching Hospital and Ain Shams Specialized Hospital in Cairo and subjected to complete history taking, clinical examination, endoscopic examination and biopsy from the lower end of esophagus for the examination of the presence of Helicobacter pylori. No causal association between infection with Helicobacter pylon and the development of [GERD] could be demonstrated