A Study of the Congenital Anomalies of the Ear with Special Reference to Microtia.

Congenital abnormalities of the ear is rare. It has been estimated that it occurs once in 2,00,000 births. Children with this malformation are usually sent to plastic surgery Dept. In bilateral cases they are often referred to E N T Dept. because of the hearing loss and the treatment becomes a combined problem. The outstanding role of radiological revaluation of the external, middle and internal ear apparatus is of paramount importance. Methods & Materials : The patients attending E.N.T., Out Patient Department was utilized as case materials. Besides clinical study, Plain X-Ray and C.T. plays an important role. C.T and plain X-Rays including lateral oblique mastoid views, Submentovertical view, Stenver’s views, Towne’s view, would be taken for assessment of external, middle and internal ear development. Whenever necessary, views for Mandible shall be recorded also. Aims and Objectivies : Objective of the present study is to classify congenital anomalies and to record the type of disabilities with the help of radiological investigations. Systemic study of incidence of such cases shall be recorded.

Efficacy of Zinc Supplementation as an Adjunct to Anti Tubercular Drug Therapy.

Zinc being a stronger electron acceptor than iron might replace iron from the critical thiol groups. So, Zinc supplementation in Tubercular Subjects might help the decompartmentalised state of iron in the body to revert back to normal compartmentalized state of iron. Again, Zinc inhibits the formation of superoxide radicals. Thus, Zinc supplementation might decrease the excess superoxide with simultaneous decrease in the formation of soluble oxygen made by dismutation reaction by the iron cofactored superoxide dismutase secreted extracellularly by the pathogenic M. tuberculosis. The study shows early and effective recovery with Zinc supplementation (50mgm. of elemental zinc orally / day for one month) along with anti - Tubercular drug therapy. This gets support by the significant changes in the serum level of three enzymes – Glutamine Synthetase, Superoxide Dismutase and Cholienesterase. Again, the dose of zinc supplementation instituted with a great benefit and without any toxic symptoms and signs, is below the Lowest Observed Adverse Effect Level (LOAEL) based on the superoxide dismutase activity in erythrocytes with zinc intake.

Treatment of Periapical Lesion with Platelet Rich Fibrin.

Periapical surgery aims to remove periapical pathology to achieve complete wound healing and regeneration of bone and periodontal tissue. Platelet rich fibrin (PRF) is a wonderful tissue engineering product and has gained much popularity due its promising results in wound healing bone induction. The features of this product are an attribute of platelet cells, which, after cellular interactions, release growth factors. This case report illustrates the use of PRF in bony regeneration after enucleation of cyst in anterior maxilla.