RÉSUMÉ
This study was done on forty patients suffering from chronic sinusitis for more than six months. They were twenty eight males and twelve females, their age ranged from 20-70 years old. The main presentation was nasal obstruction, nasal discharge and headache. All patients were submitted for case history, general and local examinations, laboratory and radiological investigations. Then all patients were submitted for collection of nasal discharge by applying nasal vasoconstrictor, then each nostrile was flushed with 20 ml, of sterile normal saline. The patient takes a deep inspiration, then forcelly exhales through the nose. The collected fluid was centrifuged and sent for culture of fungi. Tissue biopsy was taken during functional endoscopic sinus surgery from the mucous membrane of the middle meatus or from the pedicle of the removed polyp. Both nasal discharge and tissue biopsy were cultured on sterile Sabaroud's dextrose agar or modified dextrose agar. The result of this study revealed four positive cases [10%]; two cases of Aspergillus flavus, one case of Penicillium and one case of Candida albicans. All patients were submitted for Functional endoscopic sinus surgery and follow up for six months revealed recurrence of one case complete cure of the other three cases