Résumé
Objectives: Evaluation of reactive donor demographics is helpful in assessing the risk of transfusion transmittable diseases [TTDs] which assists in formation of long term strategies to improve public health, assessing quality and effectiveness of donor screening, and prevent disease spread. This study was conducted to assess the impact of education and age on sero-reactive first time and repeat blood donors in order to identify gaps between knowledge and awareness in urban replacement blood donors of a developing country
Methods: A cross sectional observational study was conducted at the blood bank of Liaquat National Hospital and Medical College, Karachi from July 2014 to June 2016. This study reviewed the demographic features of reactive blood donors during two year period. Comparative analysis of transfusion transmittable disease pattern with last 10 year data was performed. Reactive donors during the study period were grouped into first time and repeat donors and their association with different age groups, level of education and type of disease was sought using chi square test
Results: We found a sero-prevalence for HBsAg as 1.64%, HCV 2.13%, HIV1 and 2 0.10%, Syphilis 1.73%, and for Malaria as 0.005%. Trend analysis showed mild reduction in HCV reactivity for the study period. 67.3% [n=382] of first time donors and 45.8% [n=585] repeat donors belonged to the youngest age bracket of 15-29 years. Donation status was found to have significant association with age group [p
Conclusion: Our study showed that education, age, HBsAg and VDRL infectivity affects both groups of reactive donors. Continuous monitoring of donor demographics can help in assessing and revising policies for donor awareness and transfusion transmittable disease control and prevention
Résumé
Radiologically guided Fine needle aspiration cytology [FNAC] is a valuable technique for diagnosing benign and malignant space occupying masses of liver. It is a cost effective and safe method that can differentiate benign and malignant lesions accurately. The objective of this study was to analyze 404 cases of radiologically guided fine needle aspiration cytology of space occupying lesions of liver. The study was conducted at Histopathology Department SZFPGMI in collaboration with the Radiology Department. The aspirates were done by senior radiologist in Radiology Department. Most of the aspirates were from males. Five cases were considered inadequate, there were more malignant cases [295 cases] as compared to benign lesions [99 cases]. Metastatic lesions were more common as compared to hepatocellular carcinoma [HCC], however, the ratio of metastatic adenocarcinoma and primary HCC was almost equal. Thus radiologically guided FNAC is the simple, quick and complication free procedure for diagnosing space occu pying lesions of liver