Résumé
Objective: To study the bone mineral content and density in children with congenital adrenalhyperplasia (CAH). Methods: 35 children with congenital adrenal hyperplasia and 35 healthycontrols. Bone mineral content and density were studied by Dual Energy X-rayabsorptiometry. Results: The mean (SD) of lumbar spine bone mineral density (g/cm2) [0.590(0.100) vs 0.589 (0.088) (P=0.97)], total Body less head bone mineral density (g/cm2) [0.536(0.090) vs 0.548 (0.111) (P=0.64)], lumbar spine bone mineral content (g) [29.85 (27.63) vs31.03 (29.19) (P=0.86)], and total body less head bone mineral content (g) [254.27 (281.25)vs 273.07 (330.71) (P=0.79)] were not different between children with CAH and controls,respectively. Conclusion: Bone mineral density and content in children with congenitaladrenal hyperplasia are maintained in the normal range.
Résumé
Biliary diversion offers a potential option for intractable pruritus in children with chronic cholestatic disorders. Progressive familial intrahepatic cholestasis [PFIC] is an inherited disorder of impaired bile acid transport and excretion, which presents with jaundice and pruritus in the first few months of life and progresses to cirrhosis by infancy or adolescence. We report a child with PFIC type 1 who underwent internal biliary diversion for intractable pruritus and was relieved of his symptoms