Retinal Detachment as an Initial Presentation of Metastatic Breast Carcinoma – A Case Report

Ocular involvement in disseminated malignancies can present due to many reasons, most important being direct ocular infiltration by cancer cells. We present a case of choroidal metastatses. A 50-year-old female presented with sudden diminution of vision in the left associated with RAPD and deep episcleral congestion. Fundus examination revealed a solid retinal detachment and was confirmed by B-scan. Fine- needle aspiration cytology of the lymph node and retinal biopsy confirmed the features of adenocarcinoma breast. The past history confirmed the history of mastectomy and chemotherapy. She was later refereed for radiotherapy.

Central Corneal Thickness as Measured by Spectral-Domain Optical Coherence Tomography in Glaucomatous and Non-Glaucomatous Eyes

Objective: Accurate measurement of intraocular pressure (IOP) is an integral part of glaucoma diagnosis and management. IOP measurement is influenced by central corneal thickness (CCT). Aims: This study aims to compare the CCT as measured by spectral-domain (SD) optical coherence tomography (OCT) in glaucomatous and non-glaucomatous eyes and to compare the CCT in various types of glaucoma.Settings and Design: It was a prospective case–control study conducted at a tertiary hospital in Mangaluru.Materials and Methods: Patients diagnosed with primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), and ocular hypertension (OHT) were taken as cases. They underwent CCT measurement using SD-OCT anterior segment cube program after a complete ophthalmic evaluation.Statistical Analysis: Data were analyzed using SPSS for Windows, version 8.0 using Kruskal–Wallis test, Mann–Whitney U-test, and Chi-square test. P < 0.05 was considered statistically significant.Results: Forty cases (80 eyes) were included in the study, of which 26 had POAG, 12 had NTG, and 2 had OHT. Controls were 80 patients with healthy corneas. The mean CCT in POAG group was 518.69 μm, in NTG was 503.33 μm, and in OHT group 542.5 μm. The mean CCT among controls was 523.97 μm. The differences in CCT in all the four groups were statistically insignificant. The IOP was corrected for CCT and the difference between the two was statistically significant.Conclusions: CCT is higher in OHT and lower in NTG. Our study did not find any statistically significant difference between the three types of open-angle glaucoma