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Tunisie Medicale [La]. 2005; 83 (10): 635-637
Dans Français | IMEMR | ID: emr-75270

Résumé

Levosimendan is a new inodilator that improves cardiac contractility by sensitizing troponin C to calcium. This drug has proved to be effective in treating advanced congestive heart failure but has not been evaluated in cardiogenic shock. We present the case of a 54-year-old male patient treated successfully with levosimendan for cardiogenic shock following acute myocardial infarction. Treatment with dobulamine, revascularisation and intra-aortic balloon conterpulsation had first failed to improve his hemodynamic variables. Levosimendan induced a steady decline of increased pulmonary capillary wedge pressure, followed by an increase in cardiac index and mixed venous oxygen saturation. Left ventricular ejection fraction improved from 25% to 47%. Infusion of levosimendan can be used in cardiogenic shock without side effects and to improve hemodynamics and left ventricular function


Sujets)
Humains , Mâle , Cardiotoniques , Infarctus du myocarde , Processus hétérotrophes , Échocardiographie , Catécholamines
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