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Indian J Exp Biol ; 1991 Aug; 29(8): 770-2
Article Dans Anglais | IMSEAR | ID: sea-58289

Résumé

Effects of localized low (2.5 Gy) and high (10 Gy) levels of gamma irradiation on the testis of albino rats were studied. A marked increase in the testicular total lipid, phospholipid and cholesterol content was observed at all post-treatment intervals except at 16 weeks where the contents decreased. A significant decrease in the activity of acid phosphatase/g of testis was seen at both the doses, the minimum value being at 4 weeks. The decrease in acid phosphatase activity is correlated with the state of germ cell population in seminiferous tubule which is found to be depleted at 4 week interval. The alkaline phosphatase activity/g testis however, showed a significant increase, the maximum being at 4 weeks post-treatment. Thereafter, the values of the enzyme activity showed a slight recovery at 16 weeks post-irradiation. ATPase activity increased initially followed by a significant decrease at all post-treatment intervals.


Sujets)
Animaux , Rayons gamma , Métabolisme lipidique , Mâle , Phosphoric monoester hydrolases/métabolisme , Rats , Testicule/métabolisme
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