RÉSUMÉ
This study is a cross-sectional study, carried out to find out pattern of infection in pediatric oncology patients, to determine the frequency of risk factors predisposing to infection and to determine the impact of that infection on mortality of those patients. The study was conducted at the pediatric unit of the NCI; Cairo University. The study includes 175 pediatric oncology patients proved to have infection, the patients were chosen as a consecutive non-probability sample. The study revealed that the commonest focus of infection was mucositis [83.43%], followed by GIT infection [45.14%] then chest infection [26.86%]. The most common organisms were Gram positive organisms, accounting for [58.2%] of the total isolates compared to [39.8%] of Gram-negative organisms and fungal infections accounted for [13.95%] of all the isolates. The mortality rate was [10.3%] and the predicting factors for mortality were as follows: residence of the patients whether rural or urban, socioeconomic state, chest infection and intensified protocol of chemotherapy