Effects of reducing postprandial hyperglycemia and metabolism of acetate wheat starch on healthy mice

Abstract Recently, the acetate wheat starch (AWS) has been prepared by acetylation with an acetyl content of 2.42%, containing of rapidly digestible starch (RDS), slowly digestible starch (SDS) and resistant starch (RS) with 25.0%; 22.9% and 34.5%, respectively. In this study, this kind of starch was continuously evaluated with the postprandial blood glucose response and determined short-chain fatty acids (SCFAs) metabolized from AWS in the gastrointestinal tract of healthy mice by HPLC. The result showed that the mice fed with AWS exhibited a very limited increase in blood glucose level and remained stable for 2 hours after meals efficiently comparing with the control group fed with natural wheat starch (NWS). Simultaneously, the content of SCFAs produced in the caecum of the mice fed with AWS was significantly higher than mice fed with NWS, especially with acetic and propionic acids by 28% and 26%, respectively. Thus, AWS has shown to limit the postprandial hyperglycemia in mice effectively through the resistance to amylase hydrolysis in the small intestine. When going into the caecum, it is fermented to form SCFAs providing a part of energy for the body's activities, avoiding rotten fermentation causing digestive disorders which are inherent restrictions of normal high cellulose and fiber food.

Anti-inflammatory Triterpenes and Glyceryl Glycosides from Kandelia candel (L.) Druce

Phytochemical investigation of Kandelia candel resulted in the isolation of six triterpenes (1 - 5) and two glyceryl glycosides (6 and 7) and their structures were determined by comparing the spectroscopic data with those of reported values. In present study, we described the inhibitory effects of fractions and isolated compounds from K. candel on pro-inflammatory cytokines (IL-12 p40, IL-6, and TNF-alpha) production in lipopolysaccharide (LPS) stimulated bone marrow-derived dendritic cells (BMDCs). Results indicated that compounds 3, 6, and 7 showed potent inhibition on IL-6 production (IC50 values at less than 0.5 microM, respectively). Meanwhile, compounds 6 and 7 exhibited strong inhibitory effects on the production of TNF-alpha (IC50 values of 1.7 +/- 0.1 and 5.5 +/- 0.2 microM). Compounds 1 and 3 were also showed the inhibitory effects on IL-12 p40 production (IC50 values of 8.9 +/- 0.4 and 3.3 +/- 0.1 microM, respectively).

Some notes about the relationship between cytological diagnosis by fine needle aspiration biopsy method with tissue diagnosis and clinical symptoms of normal thyroid pathology

216 patients with normal functional thyroid pathology were treated at Hospital No 108 in 2000-2003 year period. For study the relationship between clinical symptoms, 44 cases underwent a biopsy with fine needle aspiration and were diagnosed as simple thyroid goiter, 162 cases had got cytological diagnosis as thyroid goiter, 8 cases as suspect of thyroid cancer. Clinical feature of 2 patients who had got fine needle aspiration cell biopsy had confirmed thyroid cancer.

Classification and antibiotic sensitive of caused bacterium in some cases of pneumonia

82 cases of pneumonia patients in the community and 3 cases at the hospital aged 62 in average, randomly collected were diagnosed bacteriologically using the samples gathered endoscopically which underwent a quantified culture and the antibiogramme was made by the method of dispersion on ager disk. Results showed that the pathogenes were mainly streptococci then gram(-) bacilli, sensitive with classic beta-lactam antibiotic group. The previous treatment by antibiotic before bacterical detection affected dramatically on the antibiotic sensitivity of pathogenic bacteria, especially with betalactam antibiotic, commonly used now a day.

Treatment of spontaneous pneumothorase by using autotranfusion to create adhesion of pleura

123 patients with spontaneous pneumothorax (including 5 patients with bilateral pneumothorax) were treated in Military Hospital No103, aged 16-83, the sex and age were concernless. The incidence of right pneumothorax (64,4%), higher than a left (31,8%). This meidence in the group of occupations requiring physical strength is higher than in the group of sedentary and intellectual occupations. The onset manifests suddenly after an effort (76,3%). Clinical symptoms are violent suddenly pain of the chest (88,6%) dyspnea in the first hours (74,1%) enlarging intercostal clift in the sick side impairing the respiratory, gillard triad (99,1%). CT scaner has big value in determining the cause of pneumothorax (coefficiency of Kppa = 0,8). The continuous aspirating draining of pleural cavity in combining with creating pleural adhesive by autotransfusion is simple, inexpensive and efficacy method of treatment

Some observations on the efficacy of cytological diagnosis with the methods of fine needle aspiration (FNA), histopathology and their clinical relations

216 patients with thyroid pathology who had normal thyroid function were studied prospective with cytology examination by FNA method at hospital 103 from the year 2000 to 2003. Among them 69% had a compatobility between cutology and histopathology results, 27,3%no and 3,7% partly. With simple thyroid goiter diagnosed on cytology, the histopathology had defined 50% had accuracy. With a suspection of thyroid cancer as diagnosed cytologically, the histopathology had defined that 62,5% had cancer, accurately