Effects of exposure to aluminum on some metal elements contents in hippocampus of rat / 中华预防医学杂志

<p><b>OBJECTIVE</b>To investigate the effects of exposure to aluminum (Al) on Zn, Fe, Cu and Ca contents in hippocampus of rats.</p><p><b>METHODS</b>AlCl(3).6H(2)O was administered orally through diet (8% of body weight) to SD rats at doses of 0 (A), 11.2 (B), 55.9 (C), 111.9 (D) mg Al(3+)/kg BW for successive 90 days. Then Al, Zn, Fe, Cu and Ca contents in hippocampi of rats were determined by atomic absorption spectrophotometry.</p><p><b>RESULTS</b>After oral exposure to Al, the Al content in hippocampus of rat increased significantly with a remarkable dose-effect relationship (r = 0.731, P < 0.001), The Zn, Fe, Ca and Cu contents in these four groups are as follows: Group A (18.29 +/- 2.48, 24.86 +/- 1.97, 48.69 +/- 22.08, 4.53 +/- 0.99) mg/g, Group B (17.22 +/- 2.06, 27.54 +/- 2.87, 42.79 +/- 14.42, 4.06 +/- 0.41) mg/g, Group C (14.46 +/- 1.90, 20.18 +/- 2.79, 29.95 +/- 7.33, 3.98 +/- 0.25) mg/g, Group D (15.85 +/- 2.54, 20.96 +/- 2.83, 36.14 +/- 12.66, 4.53 +/- 0.58) mg/g. Compared with the control group A, the Zn and Fe contents in group B and group C decreased significantly (P < 0.05), and the Ca content in group C also decreased significantly.</p><p><b>CONCLUSION</b>Oral exposure to Al may result in accumulation of Al in hippocampus of brain and thus affect some essential elements (Zn, Fe, Cu and Ca) contents in the hippocampus at different degrees.</p>

Variation of Formaldehyde Concentrations in Indoor Air of Newly Decorated Office / 环境与健康杂志

Objective To study the variation of formaldehyde concentrations in indoor air of newly decorated office room Methods 7 office rooms decorated 3 months ago were selected to be monitored every 1 5 months for 5 times, and the room temperature was measured at the same time Results During the period from the 3rd month to the 10th month after the decoration,the room temperature dropped from 14 ℃ to 10 ℃,and went up to 26 ℃ again;the average formaldehyde concentration decreased from 0 22 mg/m 3 to 0 09 mg/m 3 and then increased to 0 22 mg/m 3; the over standard rate decreased from 57 1% to 0% and then increased to 85 7% Conclusion During the course of monitoring,formaldehyde concentrations in indoor air did not decrease apparently with the prolongation of the duration after the end of the decoration,but varied according the changes in room temperature,and formaldehyde concentrations in some rooms were higher than the national hygienic standard significantly