[Ambulatory blood pressure measurement control in hypertensive treated diabetic patients]

Good blood pressure control is one of the recommended targets in diabetic patient's management.To evaluate blood pressure [BP] control in hypertensive treated diabetic patients using ambulatory blood pressure measurement [ABPM]. Two hundred and six hypertensive treated diabetic patients were enrolled in this study [83 men and 123 women]. Mean age were 60.3 +/- 9.6 years-old with mean diabetic duration of 9.1 +/- 8.2 years. All of them underwent 24 hours ABPM. Intervals between measurements were 20 minutes at diurnal period and 30 minutes at nocturnal period. 28 patients [13.6%] only were at recommended target levels of blood pressure control [mean diurnal BP < 130/80 mmHg and nocturnal BP < 115/65 mmHg] and 137 patients were at the most bed control levels [mean diurnal BP ? 140/90 mmHg or nocturnal BP ? 125/75 mmHg]. Bed controlled patients had mildly higher waist circumference [p=0.08]. Poor BP control was associated with non dipper character [p<0.001], diabetic nephropathy [p<0.01] and diabetic retinopathy [p<0.01]. Our hypertensive treated diabetic patients were far from good blood pressure control. ABPM showed that the loss of nocturnal blood pressure fall was the most associated abnormality with poor BP control. Diabetic microangiopathy were more frequent in poor controlled patients

[Role of visceral obesity in metabolic disorders associated with hyperandrogenia in Hirsute women]

The aim of our study was to evaluate the relationship between the importance of visceral fat measured by tomodensitometry and the metabolic disturbances in hirsute women. It is a prospective study where 52 women were explored for hirsutism, They underwent a clinical and biological examination, as well as an abdominal tomodensitometry at the 4th and 5th lumbar spine level to measure the area of visceral fat [VF] and sub-cutaneous fat [ScF]. In the 25 patients with VF predominance [VF/ScF >/= 0.2] age, body mass index [BMI], fasting insulin, [12h] and the prevalence of dyslipidaemia were significantly higher compared with women with ScF predominance [VF/ScF<02] There was a positive correlation between VF and age, BMI, waist to hip ratio, I2h and triglyceridemia. In conclusion, hirsute women with visceral fat predominance are at higher risk to develop the insulin resistance syndrome, So, preventive measures against cardio-vascular risk factors, like overweight, must be a part of the treatment