Anti -allergic Effects of Xitare Tab lets Combined with External Applica tion of Xitare Ointment / 中药新药与临床药理

Objective To investigate the anti -allergic effects of Xitare tablets combined with external use of Xitare Oint-3Gussinye Mment.MethodsSynlogousratmodelsofdermalsensitivity,mousemodelsofDNCB-induceddelayedhypersensitivity,ratmodelsofmastocyticdegranulationandguineapigmodelsofhistamine-phosphate-induceditchingreactionwereap-plied.ResultsXitaretablets(1.75,3.5,7.0g/kgbodyweight,bid,ig)combinedwithexternaluseofXitareOint-ment(0.7,1.4,2.1g/pertime,qd)obviouslycounteractedtheallergicreactioninratswithdermalsensitivity(P