Résumé
SUMMARY OBJECTIVE: Several prospective randomized trials have shown that hypofractionation has the same efficacy and safety as the conventional fractionation in the treatment of localized prostate cancer. There are many benefits of hypofractionation, including a more convenient schedule for the patients and better use of resources, which is especially important in low- and middle-income countries like Brasil. Based on these data, the Brazilian Society of Radiotherapy (Sociedade Brasileira de Radioterapia) organized this consensus to guide and support the use of hypofractionated radiotherapy for localized prostate cancer in Brasil. METHODS: The relevant literature regarding moderate hypofractionation (mHypo) and ultra-hypofractionation (uHypo) was reviewed and discussed by a group of experts from public and private centers of different parts of Brasil. Several key questions concerning clinical indications, outcomes and technological requirements for hypofractionation were discussed and voted. For each question, consensus was reached if there was an agreement of at least 75% of the panel members. RESULTS: The recommendations are described in this article. CONCLUSION: This initiative will assist Brazilian radiation oncologists and medical physicists to safely treat localized prostate cancer patients with hypofractionation.
Sujets)
Tumeurs de la prostate/radiothérapie , Radiothérapie conformationnelle avec modulation d'intensité , Brésil , Études prospectives , Résultat thérapeutique , Hypofractionnement de doseRésumé
A preponderância dos casos de AIDS em mulheres durante os anos reprodutivos exige atençäo dos obstetras para prevençäo primária, diagnóstico precoce e intervenções apropriadas. Os autores apresentam as principais implicaçöes entre a gestaçäo e a infecçäo pelo vírus HIV, bem como as condutas preconizadas na literatura atual
Sujets)
Grossesse , Syndrome d'immunodéficience acquise/transmission , Complications infectieuses de la grossesse/étiologie , Complications infectieuses de la grossesse/thérapie , Prise en charge prénataleRésumé
O carcinoma de endométrio é a neoplasia do trato genital feminino mais freqüente nos países desenvolvidos e tem aumentado em freqüencia no Brasil. A identificaçäo de fatores de risco e o desenvolviento de métodos de screening permite um diagnóstico precoce, o que aumenta as chances de cura. O estadiamento é realizado cirurgicamennte e permite ampla avaliaçäo da disseminaçäo sistêmica da doença