A Case of Congenital Cytomegalovirus Infection with Severe Hydrocephalus in Prenatal Ultrasonography / 대한산부인과학회잡지

Cytomegalovirus (CMV) infection is one of the most common viral infections in human and it is known to cause primary and recurrent infections. CMV is spread to the fetus in 40% of pregnancies in primary infection, while 0.5-1% of pregnancies in recurrent infection are known to cause congenital infections. Only 10% of such infections are presented with severe symptoms, with the other 90% being asymptomatic. However, there are no definite methods to predict the manifestation of fetal infections or specific treatments in such cases. Intraventricular calcification, ventriculomegaly, intraventricular adhesion, abnormal patterns of brain fissures, brain atrophy, abnormal findings of cerebellum and cisterna magna, and hyperechoic bowels can be presented by ultrasonography in CMV infection. We introduce a case of CMV infection presented as ventriculomegaly and hyperechoic bowels by ultrasonography and pathologically confirmed by autopsy.

Pregnancy and Cerebrovascular Disease / 대한산부인과학회잡지

OBJECTIVE: It is widely believed that pregnancy accounts for a significant impact upon maternal as well as fetal health. Nevertheless, the correlation between pregnancy and cerebrovasular disease has not been fully understood due to few data available in Republic of Korea. METHODS: We have reviewed clinical diagnosis and impressions of 7,879 patients who were admitted inpatients to the Korea University Anam Hospital either for delivery or for pregnancy between 1995 and 2000, retrospectively. Four identified as patients with cerebrovascular disease were analyzed with medical records, results of blood tests and radiologic tests, as well as neurologic findings. RESULTS: In 4 patients with cerebrovascular diseases, we found 2 subarachnoid hemorrhages, 1 intracranial hemorrhage, and 1 cerebral infarction. Among 7,879 inpatients, the incidences of subarachnoid hemorrhage, intracranial hemorrhage, and cerebral infarction were 0.03%, 0.01%, and 0.01% respectively. CONCLUSION: In our study, the incidence of cerebrovascular disease during pregnancy was as low as 0.05%. But cerebrovascular disease was related to maternal and fetal health, therefore much attention should be focused on the precise evaluation of the pregnancy with cerebrovascular disease.