Résumé
In this study, 18 male well-trained physical education faculty senior students were randomly selected and grouped into smoker [5 active + 4 passive] and non-smoker [9] student groups. Plasma was collected immediately before and after a single bout of endurance track running exercise. A selected number of least invasive plasma indices of muscle fatigue [lactate and activity of lactate dehydrogenase, LDH, and xanthine oxidase, XO]. Oxidative stress [thiobarbituric acid reactive substances [TBARS], nitric oxide [NO], total iron and [Fe2+]], antioxidation [total antioxidant activity [TAOA], urate, ascorbate total zinc [Zn2+] and selenium [Se2+]] and superoxide dismutase activity [SOD] were measured using atomic absorption flame photometric and colorimetric techniques. Smoking index was calculated and plasma cotinine, the endogenous nicotine metabolic indicator, was measured using ELISA technique. Exercise induced a significant increase in muscle fatigue and peroxidative indices [lactate, LDH, XO, TBARS, NO and Fe2+] and a significant decrease in Se2+, Zn2+ and ascorbate. There was a significant increase in TAOA and SOD and a nonsignificant increase in urate in the two groups. Smokers showed significantly higher basal peroxidative and lower antioxidation indices compared with nonsmokers, a picture that was exacerbated post-exercise. These changes could not be reflected significantly on the indices of exercise and cardiorespiratory endurance