Résumé
Human immunodeficiency virus [HIV], hepatitis B virus [HBV] and hepatitis C virus [HCV] are three important prevalent infections all over the world. The aim of this study was to determine seroprevalence of HIV, HBV and HCV infections and high risk behaviors in persons who referred to the behavioral counseling center of Hamadan, west of Iran. This was a cross-sectional study which was done on 379 persons who referred to the behavioral counseling center of Hamadan. All persons after obtaining the informed consent were tested for serologic markers including HBs Ag, HCV-Ab and HIV-Ab by ELISA and western blot methods. Of the 379 persons, 71.5% [271 cases] were male and 28.5% [108 cases] were female. HIV infection was reported in 4% [15] of persons. HBV and HCV infections were reported in 2.9% [11 cases] and 35.6% [135 cases], respectively. The most common high risk behaviors were injection drug user and history of prison with 52.5% [199 cases] and 40.4% [153 cases], respectively. According to the results, injection drug users and prisoners are at the highest risk for HCV, HIV and HBV infections
Sujets)
Humains , Mâle , Femelle , Études séroépidémiologiques , Études transversales , VIH (Virus de l'Immunodéficience Humaine) , Virus de l'hépatite B , Hepacivirus , Technique de Western , Hépatite B/épidémiologie , Hépatite C/épidémiologie , Test ELISA , Antigènes de surface du virus de l'hépatite B , Anticorps de l'hépatite C , Anticorps anti-VIH , Usagers de drogues , PrisonniersRésumé
Superinfection of hepatitis A in chronic hepatitis B and C may worsen the course of disease. This study attempted to study frequency of hepatitis A virus antibodies in patients with hepatitis B and hepatitis C. 115 hepatitis C and 56 hepatitis B patients who visited the Hepatitis Association of Hamedan province during 2004-2005 were enrolled. Hepatitis A virus antibodies [IgM, IgG] by ELISA, WBC, hemoglobin, platelet, AST and ALT were evaluated. 32 patients with hepatitis B and 39 patients with hepatitis C refused the study. In 71 [85.5%] patients with hepatitis B, IgG-HAV-Ab and in one patient IgM-HAV-Ab was detected. 36 [92.3%] patients with hepatitis C had IgG-anti-HAV. Due to high frequency of HAV Ab, it is preferable to evaluate patients with hepatitis B and C for HAV-Ab instead of vaccination of all patients