Inhibition of growth of subcutaneously implanted ascites tumor in strong a mice

1. Seventy-two Strong A mice (male) were pre-treated with formalin-killed EAT cells injected to the subcutis at the inter scapular area once a week for three consecutive weeks. These were challenged later with live EAT cells on the fourth week and observed for tumor growth. There was marked diminution of the tumor weights in the experimental group in comparison with those in the controls. In 29.8 percent of the experimental mice, total inhibition of EAT growth was observed2. Further studies will be done in an effort to elucidate this phenomenon. (Summary)

Studies on host resistance to cancer VI. Electrophoretic studies in health and neoplastic disease: a preliminary report

Electrophoretic studies were made on tissue extract and sera from normal strong A mice, non-pre-treated mice challenged with Ehrlich Ascites Tumor cells; mice pre-treated with formalin-killed ascites Tumor cells prior to challenge with live EAT cells; normal human beings; patients with non-neoplastic diseases; and patients with cancer. The significance of the findings were analyzed. A consideration that the changes in the pre-treated and challenged mice indicated that the development of immunity was made. (Summary)