Study of effect of malaria parasitemia on serum electrolytes in south-east Rajasthan

Background: Malaria is a life threatening disease caused by Plasmodium parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes. Aim: To study of effect of malaria parasitemia on serum electrolytes in south east Rajasthan. Materials and methods: It was a hospital based study done on malaria indoor patients from June 2017 to March 2018 in Jhalawar Medical College, Jhalawar in South East Rajasthan. The relevant history, systemic examinations and thick and thin peripheral blood smear, malaria antigen detection rapid card test was performed and serum electrolytes like sodium, potassium and calcium level were done for all patients. All patients were categorized into three groups like P.falciparum, P.vivax and mixed infection (both P.falciparum, P.vivax). Results: We observed that female was out numbered than male. Most common affected age group was 35-45 years and most of the patients came from the rural region. Severe dyselectrolytemia was noted in mixed infection (both P.falciparum and P.vivax) and P.falciparum cases. Conclusion: Serum electrolytes level are influenced by the presence of all types of malaria severely with mixed infection and P.falciparum positive cases so severe dyselectolytemia in malaria infections should be treated timely to prevent grave complications

A Comparative Prognostic Study of Acute Myocardial Infarction Thrombolysis in Diabetics Vs Non-Diabetics Using ECG as A Tool A Hospital Based Study

Background: Diabetes mellitus is one of the six primary risk factors identified for MI, others being dyslipidaemia, smoking, hypertension, male gender, and family history of atherosclerotic arterial disease. Diabetics have been shown to have poor outcome after post-thrombolysis in acute STEMI compared to non-diabetics. Objective: To Compare, Post Myocardial Infarction in Hospital Patients Prognosis After Thrombolytic Therapy In Diabetics versus Non-Diabetics. Materials and methods: This was a prospective cross sectional study done at Jhalawar Medical College and Hospital, Jhalawar on 139 patients from October 2016 to September 2017. Consecutive patients with ST segment elevation MI, who were not treated with primary angioplasty, but were thrombolysed with Streptokinase were recruited at the time of arrival in emergency department. ECG was taken at baseline and 2 hour after STK administration. Patients were divided in two groups A) Non-diabetics B) Diabetics. Total 139 patients 85 are diabetics and 54 are non-diabetics. Bhuvanesh Kumar Kahar, Sushma Pandey, Ankush Agrawal, Darab Singh, Ravindra Kumar Sharma. A Comparative Prognostic Study of Acute Myocardial Infarction Thrombolysis in Diabetics Vs Non-Diabetics Using ECG as A Tool – A Hospital Based Study. IAIM, 2018; 5(8): 41-46. Page 42 Results: In non-diabetic group (54), ST segment resolution occurred in 77.76 % patients as compared to diabetic group (85) in which only 31.76% patients had ST segment resolution. Diabetics had more complications such as recurrent chest pain, heart failure, arrhythmias, death as compared to nondiabetics. Conclusion: Diabetics with acute myocardial infarction have worse prognosis as predicted by incomplete ST segment resolution in ECG after thrombolysis.