Résumé
Solitary mastocytoma is known to occur predominantly in children below 2 years of age and onset in adulthood is rare. Lesions are hyperpigmented in the majority of cases owing to the stimulation of melanin synthesis by mast cell growth factor. We hereby report two patients with adult onset solitary mastocytoma presenting as hypopigmented plaque. The first case was a 24-year-old man who presented with a plaque on the back of the neck of 5 years duration. The second case was a 30-year-old man who had a well-defined solitary, oval 3 x 2.5 cm plaque on the nape of the neck. Stroking of lesion resulted in a wheal with flare (Darier's sign) in both cases. Systemic examination was within normal limits in both cases. Histopathology revealed a dense toluidine blue-positive infiltrate of mast cells in the upper dermis in both cases.
Sujets)
Adulte , Âge de début , Biopsie , Derme/anatomopathologie , Granulocytes éosinophiles/anatomopathologie , Humains , Hypopigmentation/anatomopathologie , Mâle , Mastocytes/anatomopathologie , Mastocytome cutané/anatomopathologie , CouSujets)
Humains , Inde , Lèpre interpolaire/complications , Mâle , Adulte d'âge moyen , Psoriasis/complicationsRésumé
Eye involvement in chronic cutaneous lupus erythematosus (CCLE) has been reported infrequently. We describe two cases of disseminated CCLE, a 50-year-old woman and a 45-year-old man, with eyelid involvement and disease duration of 4 and 20 years respectively. The first patient showed an excellent response to chloroquine while there was lack of response in the second patient.
Sujets)
Maladies de la paupière/complications , Femelle , Humains , Lupus érythémateux chronique/complications , Mâle , Adulte d'âge moyenRésumé
Bilateral lagophthalmos secondary to facial nerve is extremely uncommon. Further, the aetiology in most of these cases is of central origin unlike the peripheral involvement in leprosy. A patient of lepromatous leprosy (LL) may be euthyroid or hypothyroid on account of leprous involvement of the thyroid gland. A case of LL with bilateral lagophthalmos and hyperthyroidism is reported.
Sujets)
Adulte , Nerf facial/physiopathologie , Paralysie faciale/microbiologie , Humains , Hyperthyroïdie/complications , Lèpre lépromateuse/complications , Mâle , Mycobacterium lepraeRésumé
The case of a male patient diagnosed to have lepromatous leprosy with type 2 reaction on multibacillary multidrug therapy, with unusual, widespread involvement of genitalia in the form of plaque and nodules of leprosy over scrotum and perimeatal region of glans, necrotic lesions of erythema nodosum leprosum over scrotum, neuritis of genital branch of genitofemoral nerve bilaterally, and azoospermia, is reported.
Sujets)
Système génital de l'homme/anatomopathologie , Humains , Antilépreux/usage thérapeutique , Lèpre lépromateuse/traitement médicamenteux , Mâle , Adulte d'âge moyenRésumé
Parakeratosis pustulosa (PP) is a distinct but less commonly known skin disease, which is frequently seen, in young girls. We describe the clinical and histological features of PP in a 7 month old female baby. Further, it is stressed that unless carefully looked for, this entity may be easily misdiagnosed as chronic paronychia, acrodermatitis of Hallopeau, pustular psoriasis, atopic dermatitis, tinea pedis or dry fissured eczematoid dermatitis and mistreated subsequently.