Short Estrous Cycle Post-ovulation in Peri-pubertal Sahiwal and Jersey Crossbred Heifers

This investigation focuses on analysing the follicular dynamics exhibited during peri-pubertal period in Sahiwal and Jersey crossbred heifers. The aim of the study was to assess first ovulation in the heifers following puberty (N=20; 10 for each breed). Heifers were subjected to alternate day trans-rectal ultrasonography (TRUS) when the diameter of dominant follicle surpassed 9 mm diameter. Transrectal ultrasonography (TRUS) was performed to observe and assess first ovulation in heifers. The size of the first pre-ovulatory follicle in Sahiwal and Jersey Crossbred heifer in peri-pubertal stage was 10.52�13 and 10.15�51 mm, respectively and the corpus luteum attained its maximum size of 13.89 and 11.26 mm, was significantly different (p<0.01) at day 8.6�4 and 8.2�48 in Sahiwal and Jersey crossbred heifers, respectively. The regression of corpus luteum (CL) adjudged by the Colour Doppler initiated on 10.6�4 and 11.0�63 day for Sahiwal and Jersey crossbred heifers, respectively. Some other follicular dynamics parameters i.e. day of wave onset, number of follicles recruited, inter-wave duration along with maximum diameter of dominant follicle, day of maximum diameter, growth rate, length of growth and static phase, duration of static phase and onset of atresia was recorded, however, no significant difference (p>0.05) was recorded between breeds. On an interesting note, the next estrous cycle for heifers did not lead to ovulation despite having follicular size more than10 mm in both the breeds. Conclusion: In peroration, peri-pubertal Sahiwal and Jersey crossbred heifers had notably precocious luteal regression after first ovulation, without subsequent ovulation in next estrous cycle.

Deceptive brown adipose tissue / Journal of the ASEAN Federation of Endocrine Societies

@#A 23-year-old female presented with headache, palpitation, and hypertensive spells. There was no similar family history. Twenty-four (24) hour urine testing showed elevated normetanephrine level with normal metanephrines [metanephrines 123 mcg/24 hrs (74-297); normetanephrines 5321.16 mcg/24 hrs (73-808)]. A biochemical diagnosis of normetanephrine-secreting pheochromocytoma was made. Considering the age and urine reports, a functional scan was ordered. Imaging with 18-FDG PET CT was done which showed uptake indicative of a large left adrenal mass, as well as uptake in the mediastinal, abdominopelvic, lymph nodes and metabolically active mesenteric, peritoneal and omental thickness. This suggested a left adrenal pheochromocytoma with the possibility of an associated lymphoproliferative disorder or active lesions in brown fat. To describe these extra-adrenal lesions, a Ga-68 This work DOTANOC PET CT was obtained which showed a diffuse somatostatin receptor-expressing large soft tissue mass lesion in the left adrenal likely to be pheochromocytoma without any other lesion elsewhere in the whole body survey. This depicts the confusion created by the metabolically active brown adipose tissue (BAT) in the FDG PET scan. Brown fat is involved in non-shivering thermogenesis and is typically located in the cervical, supraclavicular, mediastinal, and abdominal regions. High uptake in the BAT can make interpretation of the FDG PET report difficult and misleading. Some precautions like avoidance of cold and beta blockers can minimize BAT uptake in FDGPET scans.

Transanal opening of the intersphincteric space (TROPIS): a novel procedure on the horizon to effectively manage high complex anal fistulas

Anal fistulas, especially complex and high fistulas, are difficult to manage. The transanal opening of the intersphincteric space (TROPIS) procedure was first described in 2017, and a high success rate of over 90% was reported in high complex fistulas. Since then, more studies and even a meta-analysis have corroborated the high efficacy of this procedure in high fistulas. Conventionally, the main focus was to close the internal (primary) opening for the fistula to heal. However, most complex fistulas have a component of the fistula tract in the intersphincteric plane. This component is like an abscess (sepsis) in a closed space (2 muscle layers). It is a well-known fact that in the presence of sepsis, healing by secondary intention leads to better results than attempting to heal by primary intention. Therefore, TROPIS is the first procedure in which, instead of closing the internal opening, the opening is widened by laying open the fistula tract in the intersphincteric plane so that healing can occur by secondary intention. Although the drainage of high intersphincteric abscesses through the transanal route was described 5 decades ago, the routine utilization of TROPIS for the definitive management of high complex fistulas was first described in 2017. The external anal sphincter (EAS) is completely spared in TROPIS, as the fistula tract on either side of the EAS is managed separately—inner (medial) to the EAS by laying open the intersphincteric space and outer (lateral) to the EAS by curettage or excision.

Epidemiology of Traumatic Spinal Cord Injury in the Himalayan Range and Sub-Himalayan region: A Retrospective Hospital Data-Based Study

Objective@#To compile epidemiological characteristics of traumatic spinal cord injury (TSCI) in the Northern Indian Himalayan regions and Sub-Himalayan planes. @*Methods@#The present study is a retrospective, cross-sectional descriptive analysis based on hospital data conducted at the Department of Physical Medicine and Rehabilitation and Spine Unit of Trauma Centre in a tertiary care hospital in Uttarakhand, India. People hospitalized at the tertiary care center between August 2018 and November 2021 are included in the study sample. A prestructured proforma was employed for the evaluation, including demographic and epidemiological characteristics. @*Results@#TSCI was found in 167 out of 3,120 trauma patients. The mean age of people with TSCI was 33.5±13.3, with a male-to-female ratio of 2.4:1. Eighty-three participants (49.7%) were from the plains, while the hilly region accounts for 50.3%. People from the plains had a 2.9:1 rural-to-urban ratio, whereas the hilly region had a 6:1 ratio. The overall most prevalent cause was Falls (59.3%), followed by road traffic accidents (RTAs) (35.9%). RTAs (57.2%) were the most common cause of TSCI in the plains’ urban regions, while Falls (58.1%) were more common in rural plains. In both urban (66.6%) and rural (65.3%) parts of the hilly region, falls were the most common cause. @*Conclusion@#TSCI is more common in young males, especially in rural hilly areas. Falls rather than RTAs are the major cause.

Sarcopenia is common in ulcerative colitis and correlates with disease activity

Background/Aims@#Association of sarcopenia with disease severity in ulcerative colitis (UC) is not clearly defined. We planned to estimate the prevalence of sarcopenia in patients with UC as per the revised definition and its relation with the disease severity. @*Methods@#A cross-sectional assessment of sarcopenia in patients with UC was performed. Disease activity was graded according to complete Mayo score. Hand grip strength was assessed with Jamar hand dynamometer, muscle mass using a dual energy X-ray absorptiometry scan, and physical performance with 4-m walk test. Sarcopenia was defined as a reduction of both muscle mass and strength. Severe sarcopenia was defined as reduced gait speed in presence of sarcopenia. @*Results@#Of 114 patients (62 males, mean age: 36.49±12.41 years), 32 (28%) were in remission, 46 (40.4%) had mild-moderate activity, and 36 (31.6%) had severe UC. Forty-three patients (37.7%) had probable sarcopenia, 25 (21.9%) had sarcopenia, and 14 (12.2%) had severe sarcopenia. Prevalence of sarcopenia was higher in active disease (2 in remission, 6 in active, and 17 in severe, P<0.001). Of 14 with severe sarcopenia, 13 had severe UC while 1 had moderate UC. On multivariate analysis, lower body mass index and higher Mayo score were associated with sarcopenia. Of 37 patients with acute severe colitis, 16 had sarcopenia. Requirement of second-line therapy was similar between patients with and without sarcopenia. On follow-up (median: 18 months), there was a non-significant higher rate of major adverse events in those with sarcopenia (47.4% vs. 33.8%, P=0.273). @*Conclusions@#Sarcopenia and severe sarcopenia in UC correlate with the disease activity.

Adequacy of sigmoidoscopy as compared to colonoscopy for assessment of disease activity in patients of ulcerative colitis: a prospective study

Background/Aims@#Patients of ulcerative colitis (UC) on follow-up are routinely evaluated by sigmoidoscopy. There is no prospective literature to support this practice. We assessed agreement between sigmoidoscopy and colonoscopy prospectively in patients with disease extent beyond the sigmoid colon. @*Methods@#We conducted a prospective observational study at a tertiary care institute for agreement between sigmoidoscopy and colonoscopy. We assessed endoscopic activity using the Mayo Endoscopic Score (MES) and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and histological activity using the Nancy Index (NI), Robarts Histopathology Index (RHI), and Simplified Geboes Score (SGS). @*Results@#Sigmoidoscopy showed a strong agreement with colonoscopy for MES and UCEIS with a kappa (κ) of 0.96 and 0.94 respectively. The misclassification rate for MES and UCEIS was 3% and 5% respectively. Sigmoidoscopy showed perfect agreement (κ = 1.00) with colonoscopy for assessment of the presence of endoscopic activity in the colon using MES ≥ 1 as activity criteria and strong agreement (κ = 0.93) using MES > 1 as activity criteria. Sigmoidoscopy showed strong agreement with colonoscopy for assessment of the presence of endoscopic activity using UCEIS (κ = 0.92). Strong agreement was observed between sigmoidoscopy and colonoscopy using NI (κ = 0.86), RHI (κ = 1.00), and SGS (κ = 0.92) for the detection of histological activity. The misclassification rate for the detection of histological activity was 2%, 0%, and 1% for NI, RHI, and SGS respectively. @*Conclusions@#Sigmoidoscopy showed strong agreement with colonoscopy for endoscopic and histologic disease activity. Sigmoidoscopy is adequate for assessment of disease activity in patients with UC during follow-up evaluation.

Chronic abdominal wall sinus secondary to missed spilled gallstones in laparoscopic cholecystectomy:a harrowing experience

Gallbladder perforation with spillage of gallstones is not uncommon during laparoscopic cholecystectomy. Stone spillage can cause several complications. We report a case of recurrent discharging sinuses on the right back 4 years after laparoscopic cholecystectomy in a 44-year-old female patients. She suffered for 9 years to undergo empirical treatment for suspected tuberculosis, including repeated attempts at sinus tract excision done at different hospitals. We did a computed tomography sinogram, which revealed the tract extending from the right flank into a cavity in the right subpleural space. We proceeded with the sinus tract excision which extended between the tips of the 10th and 11th ribs, spreading to the right subpleural space where pus mixed with multiple gall stones were retrieved. Spilled stones may result in complications, making diagnosis difficult and seriously harming the patient physically, mentally, and economically. The need for accurate documentation and patient knowledge of missing gallstones cannot be understated.

Synthesis, antimicrobial activity and Molecular docking study of some novel isoxazole incorporated benzimidazole derivatives

A series of novel isoxazole-incorporated benzimidazole derivatives was synthesized and investigated for antimicrobial activity. The structures of all synthesized compounds were confirmed by means of elemental analysis, infrared spectroscopy (IR), proton nuclear magnetic resonance (1H-NMR), and liquid chromatography-mass spectrometry (LC-MS). All compounds were evaluated for antimicrobial activity cup plate method against Staphylococcus aureus, Bacillus anthracis, Pseudomonas aeruginosa, Escherchia coli, Candida albicans and Aspegillus niger. The 4d, 4f and 4j compounds showed significant activity against gram-positive and gram-negative bacteria. On the basis of the interaction energy criterion, compound 4f showed the best docking interactions equal to 7.0 kcal/mol.

The effects of lifestyle changes like diet, toilet habits, physical activity and others in children with functional constipation

Background: Functional constipation is common in pediatric age group. Our aim is to evaluate the effects of lifestyle changes (diet, toilet habits, physical activity and others) in children with functional constipation, and to assess the risk factors of functional constipation in Indian children.Methods: This was an observational, prospective, questionnaire and proforma based (pretested and predesigned) follow-up study. Duration was from January 2016 to December 2017. Study was conducted at, department of paediatrics, Mahatma Gandhi Medical College, Jaipur.Results: On regular follow-up, stool frequency was improved after changing the lifestyle factors like adequate physical activity (p<0.05, CI: 0.27) and regular toilet habits (p<0.05, CI:0.93), blood/mucus, straining, painful defecation and pain abdomen, all are showing significant improvement (p<0.05) after relieving constipation. On regular follow-up Need of disimpaction (polyethylene glycol or proctoclys enema) reduced significantly (p=0.001), number of cases with adequate fiber diet improved significantly (p=0.001), Number of children consuming frequent junk food decreased significantly (p=0.001). Conclusions: Initial disimpaction, if needed and maintenance laxative therapy (1-3 months as per need) along with major lifestyle changes like fibers rich diet, avoidance of junk food, adequate physical activity, optimal sleep hygiene, and daily regular toilet habits have significantly positive correlation with improvement in functional constipation and its symptoms.

Evaluation of Ivy Gourd (Coccinia grandis L) Genotypes under Prayagraj Agro Climatic Conditions

The present investigation entitled “Evaluation of Ivy gourd (Coccinia grandis L) genotypes under Prayagraj agro climatic conditions” was carried out from October, 2022 to March 2023 at Horticultural Research Field, Department of Horticulture, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, Technology And Sciences, Prayagraj, U.P. The experiment was laid out in randomized block design with seven genotypes in three replications. The genotypes namely G1-Arka Neelachal Khunki, G2-Arka Neelachal Sabuja, G3-Local Geda, G4-Local Denga, G5-Surekha, G6- CHIV-7 and G7-CHIV-8 were evaluated. It was concluded that all seven genotypes showed a significant performance on almost all the growth and yield characters as well as quality of Ivy gourd. The genotype G2-Arka Neelachal Sabuja was found superior in terms of vine length (315.11 cm), petiole length (6.37 cm), internodal length (12.71cm),fruit diameter (2.87 cm), average fruit weight (21.08 g), No. of seeds per fruit (122), No. of fruits per plant (422), fruit yield per plant (8.82 kg) ,fruit yield per hectare (17.35 t/ha), TSS (4.33), Ascorbic acid (15.34 mg/100g) and minimum days taken for first female flower anthesis (35.17 days) whereas maximum fruit length was obtained from genotype G1- Arka Neelachal Khunki (6.12 cm). Among the genotypes, highest gross return (Rs/ha) (3,47,000), net return (Rs/ha) (1,90,140), benefit cost ratio (2.21) was also obtained from genotype G2 i.e Arka Neelachal Sabuja.

Scientific Approaches for Mass Production, Cold Storage and Release of Trichogramma: Their Role in Insect Pest Management

The use of Trichogramma as a tool in the scientific management of pest insects emerges as a vital element to promote sustainability in agriculture. Having suitable storage methods for parasitoids is a valuable asset within biological control programs. The quality of Trichogramma is affected by cold storage with an acclimation period. Prepupae were subjected to storage for 50, 75, and 100 days at 5°C, preceded by acclimation periods of 10 or 20 days at 12°C. The research revealed the potential to halt the development of Trichogramma. Treatments with a 10-day acclimation period resulted in emergence values below 10%, rendering them unsuitable for establishing a cold storage protocol. In contrast, a 20-day acclimation period benefitted cold storage tolerance for the 50- and 75-day storage periods. The storage of Trichogramma, using a 20-day acclimation period and up to 50 days under cold temperatures, did not adversely affect adult emergence, emergence time, sex ratio, parasitism, or progeny quality.

Genotype x Environment Interaction and Yield-Stability Analysis of Rice (Oryza sativa L.) Grown in Salt Affected Soil

This study was conducted during Kharif, 2019 At the Students Instructional Farm, MES and Agronomy Farm of A.N.D.U.A.T., Kumarganj, Ayodhya, the trials were set up in RBD with three replications. The experimental material comprised of 25 genotypes of rice were evaluated for 11 quantitative traits under three different environmental locations. High significant mean squares were found for all eleven research characteristics in the environment-specific analysis of variance and the pooled analysis of variance for three environments encompassing one crop season. T-3, Kavery Sampoorna, NDRK-11-27, Moti Gold, and NDRK-11-29 under irrigated circumstances were the genotypes demonstrating high mean performance for grain yield per plant and some of its significant components when considering the mean performance of genotypes under various environmental situations. Out of 25 genotypes tested in three conditions, T-3, Kavery Sampoorna, and NDRK-11-27 had the maximum grain yield per plant.In path coefficient analysis highest positive direct effects on grain yield per plant was exerted by L/B ratio (0.281), followed by panicle length (0.167), number of fertile spikelet per plant (0.092) and days to 50% flowering (0.037). On the other hand, negative direct effects on grain yield per plant was exerted by plant height (-0.255), leaf area index (-0.195), spikelet fertility (-0.187), biological yield per plant and harvest index (-0.126) and productive tillers / plant (-0.049). Positive indirect effects on spikelet fertility was recorded via biological yield per plant (0.040) followed by panicle length via biological yield per plant (0.264), productive tiller per plant biological yield per plant (0.021) and plant height via biological yield per plant (0.011).Considering the mean performance and stability parameters, three high yielding genotypes T-3, Kavery Sampoorna and NDRK-11-27 merit due consideration for recommending their exploitation as cultivars or varieties for commercial cultivation and/or as donor for hybridization programme for wide range of environments pertaining especially to different environments. In addition to these genotypes, several other genotypes exhibiting high or average mean performance, desirable non- linear response and stable nature for different characters may also be useful for exploitation as parents in hybridization programme as donors for characters for which they showed superiority even if they had average or low grain yield per plant.

A Comprehensive Review on Seasonal Incidence of Fall Army Worm, Spodoptera frugiperda (J.E. Smith) and Their Management

The Fall Armyworm (FAW), Spodoptera frugiperda, represents a formidable challenge to global agriculture due to its rapid spread and significant impact on crop yields. This comprehensive review focuses on providing an in-depth exploration of FAW's biology, its seasonal dynamics, and the multifaceted strategies employed for its management. Leveraging datasets from multiple geographical regions, we examined the patterns of FAW infestations and their correlation with various climatic and environmental factors. The research emphasized the criticality of predictive modeling tools in forecasting pest incidence and highlighted the potential of machine learning and big data analytics in enhancing the accuracy of these predictive tools. Innovative management solutions, spanning from genetic interventions to the application of nanotechnology, were also discussed, underlining their potential in mitigating FAW damage. Central to our findings was the recurrent theme of international collaboration; the need for globally coordinated efforts in research, monitoring, and the sharing of resources emerged as a pivotal component in the fight against this pest. By incorporating diverse perspectives, including field insights from farmers and advancements in modern technology, this review aims to provide a holistic overview of the present scenario and proffers strategies for future action against the FAW threat.

CLINICAL PROFILE AND TREATMENT RESPONSE TO SOFOSBUVIR-VELPATASVIR REGIMEN AND ITS IMPACT ON THE QUALITY OF LIFE IN CHRONIC HEPATITIS C PATIENTS

Objective: Chronic Hepatitis C infection is one of the major global contributors to liver-related morbidity and mortality. Successful antiviral therapy with the direct-acting antiviral combination sofosbuvir-velpatasvir has shown to improve survival, liver-related outcomes, all-cause mortality, and even reverse fibrosis. We evaluated the treatment response of this regimen in terms of its impact on the Quality of life of patients during and after the therapy.Methods: This is an Observational, prospective, descriptive study of serologic HCV RNA-positive cases. Data on change in clinical, biochemical profile, and quality of life using 2 standardized questionnaires SF-36 and CLDQ was analyzed at baseline, 12 w from baseline, and 24 w after therapy cessation.Results: 62 out of the 87 patients registered during the study completed the desired study duration. 95% achieved sustained virological response (SVR) at 12 w and 100% at 24 w from baseline. Improved clinical profile with symptom resolution and change in the biochemical parameters and quality-of-life scores was statistically significant (P value-<0.001 and 0.005) at 12 w from baseline and 24 w after therapy cessation, respectively.Conclusion: Patients achieving SVR with sofosbuvir-velpatasvir have been shown to improve clinical profile with normalization in biochemical markers of liver disease, which is reflected in all the quality-of-life domains of SF-36 and CLDQ-HCV. However, long-term follow-up with larger sample size is required for improved study validity and to improve long-term liver-related outcomes.

Obstructive Sleep Apnea and Hearing Loss: Is There Any Correlation?

Abstract Introduction Obstructive sleep apnea (OSA) is a breathing disorder related to sleep that has a negative effect on the behavior and health of people around the globe. Chronic hypoxemia and variations in the concentration of oxygen in the blood noticed in OSA individuals may have adverse effects on the process of auditory transduction and transmission. Objective To assess the effect of OSA on hearing and to find out the parameters that have more influence on hearing recorded during polysomnography of patients with OSA. Methods The present is a hospital-based, observational, analytical, cross-sectional study conducted over a period of one year. After application of the exclusion criteria, the patients were then submitted to the application of the Berlin questionnaire, as well as polysomnography, impedance, and pure tone audiometry (PTA). Results A total of 58 individuals were studied. Age, gender, and height were comparable among cases and controls, while weight, body mass index (BMI), and neck circumference were significantly higher in cases in comparison to controls. The mean PTA was significantly higher at 10 kHz or higher frequencies in cases in comparison to controls. Conclusion We observed that there is evidence that the auditory mechanism is affected in OSA patients. We recommend early auditory screening of OSA patients for timely diagnosis and to raise awareness about its prevention.

Implication of Jasmonic Acid on Physiological Alterations on Salt Stressed Fodder Sorghum (Sorghum bicolor L.)

One of the main environmental factors that restricts the growth and productivity of sorghum is salt stress, which interferes with physiological processes including relative water content, NBI (nitrogen balance index), photosynthetic rate, etc. Agricultural land affected by soil salinity is growing significantly worldwide, therefore, strategies are needed to improve the salinity tolerance and most efficient one can be opted by studying the response of sorghum against salinity. Salt stress can be reduced by plant stress hormones such jasmonates, ABA, brassinosteroids, etc. In order to assess the effects of jasmonic acid (JA) (4.5, 6.5 & 8.5 mM) on the physiological properties of sorghum (HJ 541 and CSV 21F) grown in saline soil (4, 6 & 8 dS/m), green house experiment was executed on a complete randomized design (CRD), with three replications. The results shows that the salinity adversely effected photosynthetic efficiency, chlorophyll content, antioxidants (anthocyanin and flavonoids), nitrogen balance index, ash content which can be used as the most suitable parameter for determining tolerance to salinity stress. While, foliar application of jasmonic acid significantly improved the relative water content, chlorophyll content, photosynthetic rate, stomatal conductance, etc. Jasmonic acid concentrations of 8.5 mM had more noticeable effects. Percent enhancement in chlorophyll index, transpiration rate, stomatal conductance, was 14.5% and 13.4%, 16.7% and 19.9%, 42.0% and 58.0% in HJ 541 and CSV 21F, respectively at 8 dS/m as compared to control. CSV 21F performed better as compared to HJ 541 at all levels of salt stress after application of jasmonic acid.

Abundance of Major Insect Pests in Rice and Their Relation to Weather Parameters

The present investigation has been conducted in rice crop during Kharif 2021-22at Students’ Instructional Farm of Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya (U.P.), India. The population of six major insect pests was recorded viz. Rice Yellow stem borer (Scirpophaga incertulus), Rice Leaf folder (Cnapholocrocis medinalis), Rice ear head bug (Leptocorisa acuta), Brown plant hopper (Nilaparvata lugens), White backed plant hopper (Sogatella furcifera)and Green leaf hopper (Nephotettix nigropictus) that cause most damage at different crop growth stages initiated after sowing till harvesting. The maximum population of yellow stemborer was observed on rice crop at 36th SMW (12.20 per cent dead heart). The infestation of dead heart was non-significant positively correlated with minimum, maximum temperature and RH% (0.433, 0.010 & 0.253 respectively) and negatively correlated with rain fall (0.081) whereas, significant negatively correlated with sunshine (0.552*). The maximum population white ear in 40th SMW (16.80 per cent). The infestation of white ear was non-significant negative correlation with minimum, maximum temperature (-0.062, -0.167) and positive correlation with RH & rain fall (0.244 & 0.173) whereas, significant positive correlation with sunshine (0.703*). Maximum leaf folder population was observed during 35th SMW (16.35 per cent). and infestation of leaf folder was non-significant positive correlation with minimum temperature & RH (0.427 & 0.505) and negative correlation with maximum temperature, rainfall and sunshine (-0.079, -0.030 & -0.291). The maximum population was recorded of ear head bug in 38th SMW i.e., (10.90 ear head bug/hill respectively.). The infestation of ear head bug was non-significant positive correlation with minimum temperature, RH, rainfall & sunshine (0.061, 0.176, 0.155 & 0.210) and negative correlation with maximum temperature (-0.407). The peak mean population of BPH was recorded in 37th SMW i.e., (11.25 brown plant hopper/hill respectively.) Itwas non-significant positive correlation with minimum temperature & RH (0.463 & 0.357) and negative correlation with maximum temperature & rainfall (-0.066 & -0.088) whereas, significant negative correlation with sunshine (-0.597*), The peak mean population of WBPH was recorded in 38th SMW i.e., (12.80 white backed plant hopper/hill respectively.) It was non-significant positive correlation with minimum temperature, RH & rainfall (0.300, 0.337 & 0.185) and negative correlation with maximum temperature (-0.300) whereas, significant negative correlation with sunshine (-0.094*) and the maximum population of green leaf hopper was recorded in 37th SMW i.e., (10.80 green leaf hopper/hill respectively.) with the infestation of green leaf hopperwas non-significant positive correlation with minimum temperature & RH (0.479 & 0.369) and negative correlation with maximum temperature & rainfall (-0.077 & -0.120) whereas, significant negative correlation with sunshine (-0.633*).

Efficacy of Insecticides against Major Insects of Tomato in Manipur

A field experiment was conducted to evaluate the efficacy of some insecticides viz., Emamectin benzoate 5% SG (11 ga.i./ha), imidacloprid 17.8% SL (22.5 g a.i/ha), Neem oil (3 ml/l), Beauveria bassiana (0.2 ml/l), fipronil 5% SC (50 g a.i/ha) against major pests of tomato (Lycopersicon esculentum Mill.). There were six treatments arranged in randomized block design with four replications. Fruit borer, whiteflies, aphids and leaf miner were found to be the major insect pests of tomato. Among the insecticide used, imidacloprid 17.8% SL was found to be the most effective for management of sucking pest viz., Whiteflies, Aphids, Thrips, Mealybugs, Jassids while emamectin benzoate was found more effective on tomato fruit borer. Beauveria bassiana was found least effective against all the insect pests.

Physiological Responses of Wheat Associate with Heat Tolerance

This study was performed to explore heat stress tolerance indices to judge terminal heat tolerance genotypes from nine wheat genotypes viz: AKAW 5023, AKAW 4927, PBN 4905, PBN 4751-02, NIAW 3523, NIAW 2891, AKAW 4210-6 (C), NIAW 34 (C), NIAW 1994 (C) at Wheat Research Unit, Dr. Panjabrao Deshmukh Krishi Vidyapeeth, Akola (MH) during Rabi 2016-17 and 2017-2018. The trial was setup in RBD design with three replications. Yield and Physiological traits were recorded and correlated with yield. Genotype NIAW 2891 noted significantly high germination %,CTD (4.30oC), minimum membrane thermo-stability index (48.86%) at 75 DAS (grain filling stage), exhibited more RGR (0.0074 g g-1 day-1), NAR (0.0500 g dm2 day-1), early 50% flowering (58.16 days), days to maturity (91.83 days) and more grain yield ha-1 (35.65 q/ha) followed by genotype NIAW 3523 (33.83 q/ha) during both the year and noted as heat tolerance genotypes against the best check AKAW 4210-6. Correlation analysis showed that yield under stress environment had positive significant correlate with days to 50 % flowering and physiological maturity however, canopy temperature and membrane thermo-stability index had negative significant correlation with yield. Hence, due emphasis should be given to these attributes for genetic improvement in wheat under heat stress condition.

Clinical profile, management and post operative outcome in patients with anorectal malformations

Background: Anorectal malformations (ARM) form a very important group of anomalies dealt by pediatric surgeons. Identification of different forms of the anomaly, planning investigation and definitive surgical procedure to attain the final goal of a continent child, remains a difficult task till date. Aim of the study was to study complete clinical profile of the ARM patient, surgical procedure and post operative outcome with special emphasis on continence.

Methods: We conducted a study at Geetanjali medical college, Udaipur, Rajasthan, India for clinical profile and management of patients with ARM with assessment of post-operative outcome. All cases of ARM operated from August 2016 to June 2021 were included in the study. All aspects of the anomaly i.e., type, age and sex distribution, associated anomalies, surgical technique used and post op complications were assessed. Evaluation of continence was done by Kelly's scoring system.

Results: The 71% patients had staged surgery with posterior sagittal ano-rectoplasty (PSARP) being the most common procedure used (71%). Immediate post op complications were nil. Incontinence was present in 29% patients. Constipation was present in 46% patients. On assessing Kelly's scoring 96% patients had satisfactory score. Postoperative continence was achieved in 70.8% and in 83.3% patients after treatment (bowel management).

Conclusions: Meticulous planning and surgical technique with sphincter identification and proper placement of ano-rectum are most important to achieve desired results. Kelly's scoring is important to assess post operative results and plan management for incontinence. With aggressive bowel management it is possible to achieve reasonable continence and quality of life for even those anomalies with poor prognosis.